Solid variant of primary effusion lymphoma in successfully treated HIV infection: A case report

E. Mylona, I. G. Baraboutis, O. Georgiou, D. Rondogianni, L. J. Lekakis, V. Papastamopoulos, I. Apostolidis, A. T. Skoutelis

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

Primary effusion lymphoma (PEL) is a unique form of non-Hodgkin lymphoma, mainly met in severely immunocompromised, HIV-positive patients. PEL is aetiologically related to human herpes virus-8 (HHV-8) and it usually presents as a lymphomatous body cavity effusion in the absence of a solid tumour mass. Recently, cases of HIV-positive patients with HHV-8-positive solid tissue lymphomas, not associated with an effusion, have been reported (solid variant of PEL). The prognosis of PEL is reported to be poor. We report a case of an HIV-positive patient with a typical solid variant of PEL without effusion. Interestingly, his disease developed while being on stable antiretroviral therapy (ART) with high CD4 counts. He had a relatively long survival with chemotherapy and ART.

Original languageEnglish (US)
Pages (from-to)570-572
Number of pages3
JournalInternational Journal of STD and AIDS
Volume19
Issue number8
DOIs
StatePublished - Aug 1 2008
Externally publishedYes

Keywords

  • HHV-8
  • HIV
  • Non-Hodgkin lymphoma
  • Primary effusion lymphoma
  • Solid variant of primary effusion lymphoma

ASJC Scopus subject areas

  • Dermatology
  • Public Health, Environmental and Occupational Health
  • Microbiology (medical)
  • Immunology

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