Small molecules and small molecule drugs in regenerative medicine

Baisong Lu, Anthony Atala

Research output: Contribution to journalReview article

29 Scopus citations

Abstract

Regenerative medicine is an emerging, multidisciplinary science that aims to replace or regenerate human cells, tissues or organs, to restore or establish normal function. Research on small molecules and small molecule drugs in regenerative medicine is currently increasing. In this review, we discuss the potential applications of small molecules and small molecule drugs in regenerative medicine. These include enabling novel cell therapy approaches and augmentation of endogenous cells for tissue regeneration, facilitating the generation of target cells for cell therapy, improving the interactions between cells and biomatrices for tissue engineering, and enhancing endogenous stem cell function for tissue regeneration. We also discuss the potential challenges for small molecule drugs in regenerative medicine.

Original languageEnglish (US)
Pages (from-to)801-808
Number of pages8
JournalDrug Discovery Today
Volume19
Issue number6
DOIs
StatePublished - Jun 2014

ASJC Scopus subject areas

  • Pharmacology
  • Drug Discovery

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