Small cell carcinoma of the renal pelvis: A clinicopathological, morphological and immunohistochemical study of 2 cases

H. Essenfeld, J. C. Manivel, P. Benedetto, J. Albores-Saavedra

Research output: Contribution to journalArticle

40 Scopus citations

Abstract

Two women, 62 and 66 years old, with combined small cell carcinoma and transitional cell carcinoma of the renal pelvis are reported. The clinical picture was similar to that seen in conventional transitional cell carcinoma. A brief review of the literature indicates that in the urinary tract, small cell carcinoma occurs most commonly in the bladder and is exceedingly rare in the renal pelvis; only 2 cases have been reported previously. The morphological spectrum of the small cell carcinomatous component is similar to that seen in lung tumors. Neuroendocrine differentiation of the small cells carcinoma component was supported by a positive immunoreaction to neuron-specific enolase in both cases and to synaptophysin in 1. One patient died with metastases 8 months after diagnosis, and 1 was alive with clinical evidence of lymph node metastases and contralateral papillary transitional cell carcinoma of the renal pelvis 16 months after diagnosis.

Original languageEnglish (US)
Pages (from-to)344-347
Number of pages4
JournalJournal of Urology
Volume144
Issue number2 I
DOIs
StatePublished - Jan 1 1990

ASJC Scopus subject areas

  • Urology

Fingerprint Dive into the research topics of 'Small cell carcinoma of the renal pelvis: A clinicopathological, morphological and immunohistochemical study of 2 cases'. Together they form a unique fingerprint.

Cite this