Small bowel and multivisceral transplantations

Tomoaki Kato, Seigo Nishida, Andreas Tzakis

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Small intestine transplantation is an evolving surgical procedure used in the management of intestinal failure in children and adults. Their outcomes have dramatically improved in recent years, with overall patient survival in both children and adults at 1 year reaching approximately 70-80%. The world registry collected just under 1000 cases as of 2003, and approximately 120 cases are added to the registry each year. Acute rejection of the small bowel remained the most disturbing problem in the treatment of patients undergoing these procedures. Substantial progress has been made recently in improving patient and graft survival rates after these procedures; this progress is largely the result of improvement in techniques for monitoring rejection and of new strategies for immunosuppression. This article summarizes recent advances in this field of transplantation, including selection of the graft, immunosuppression strategies, and methods of monitoring rejection. It also provides an algorithm of patient referral to transplant centers.

Original languageEnglish
Pages (from-to)47-54
Number of pages8
JournalTransplantation Reviews
Volume19
Issue number1
DOIs
StatePublished - Jan 1 2005

Fingerprint

Transplantation
Immunosuppression
Registries
Transplants
Graft Survival
Small Intestine
Referral and Consultation
Survival Rate
Survival
Therapeutics

ASJC Scopus subject areas

  • Transplantation

Cite this

Small bowel and multivisceral transplantations. / Kato, Tomoaki; Nishida, Seigo; Tzakis, Andreas.

In: Transplantation Reviews, Vol. 19, No. 1, 01.01.2005, p. 47-54.

Research output: Contribution to journalArticle

Kato, Tomoaki ; Nishida, Seigo ; Tzakis, Andreas. / Small bowel and multivisceral transplantations. In: Transplantation Reviews. 2005 ; Vol. 19, No. 1. pp. 47-54.
@article{49f72075b208452c970a24bbb817b341,
title = "Small bowel and multivisceral transplantations",
abstract = "Small intestine transplantation is an evolving surgical procedure used in the management of intestinal failure in children and adults. Their outcomes have dramatically improved in recent years, with overall patient survival in both children and adults at 1 year reaching approximately 70-80{\%}. The world registry collected just under 1000 cases as of 2003, and approximately 120 cases are added to the registry each year. Acute rejection of the small bowel remained the most disturbing problem in the treatment of patients undergoing these procedures. Substantial progress has been made recently in improving patient and graft survival rates after these procedures; this progress is largely the result of improvement in techniques for monitoring rejection and of new strategies for immunosuppression. This article summarizes recent advances in this field of transplantation, including selection of the graft, immunosuppression strategies, and methods of monitoring rejection. It also provides an algorithm of patient referral to transplant centers.",
author = "Tomoaki Kato and Seigo Nishida and Andreas Tzakis",
year = "2005",
month = "1",
day = "1",
doi = "10.1016/j.trre.2004.12.001",
language = "English",
volume = "19",
pages = "47--54",
journal = "Transplantation Reviews",
issn = "0955-470X",
publisher = "W.B. Saunders Ltd",
number = "1",

}

TY - JOUR

T1 - Small bowel and multivisceral transplantations

AU - Kato, Tomoaki

AU - Nishida, Seigo

AU - Tzakis, Andreas

PY - 2005/1/1

Y1 - 2005/1/1

N2 - Small intestine transplantation is an evolving surgical procedure used in the management of intestinal failure in children and adults. Their outcomes have dramatically improved in recent years, with overall patient survival in both children and adults at 1 year reaching approximately 70-80%. The world registry collected just under 1000 cases as of 2003, and approximately 120 cases are added to the registry each year. Acute rejection of the small bowel remained the most disturbing problem in the treatment of patients undergoing these procedures. Substantial progress has been made recently in improving patient and graft survival rates after these procedures; this progress is largely the result of improvement in techniques for monitoring rejection and of new strategies for immunosuppression. This article summarizes recent advances in this field of transplantation, including selection of the graft, immunosuppression strategies, and methods of monitoring rejection. It also provides an algorithm of patient referral to transplant centers.

AB - Small intestine transplantation is an evolving surgical procedure used in the management of intestinal failure in children and adults. Their outcomes have dramatically improved in recent years, with overall patient survival in both children and adults at 1 year reaching approximately 70-80%. The world registry collected just under 1000 cases as of 2003, and approximately 120 cases are added to the registry each year. Acute rejection of the small bowel remained the most disturbing problem in the treatment of patients undergoing these procedures. Substantial progress has been made recently in improving patient and graft survival rates after these procedures; this progress is largely the result of improvement in techniques for monitoring rejection and of new strategies for immunosuppression. This article summarizes recent advances in this field of transplantation, including selection of the graft, immunosuppression strategies, and methods of monitoring rejection. It also provides an algorithm of patient referral to transplant centers.

UR - http://www.scopus.com/inward/record.url?scp=17444366982&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=17444366982&partnerID=8YFLogxK

U2 - 10.1016/j.trre.2004.12.001

DO - 10.1016/j.trre.2004.12.001

M3 - Article

AN - SCOPUS:17444366982

VL - 19

SP - 47

EP - 54

JO - Transplantation Reviews

JF - Transplantation Reviews

SN - 0955-470X

IS - 1

ER -