Slow Coagulation Transscleral Cyclophotocoagulation for Post-Vitrectomy Patients with Silicone Oil-Induced Glaucoma

Mohamed M. Khodeiry, Xiangxiang Liu, Huda Sheheitli, Mohamed S. Sayed, Richard K. Lee

Research output: Contribution to journalArticlepeer-review


Precis: Slow coagulation transscleral cyclophotocoagulation is an effective and safe glaucoma surgery in patients with medically uncontrolled silicone oil-induced glaucoma. Purpose: To report the outcomes of slow coagulation continuous wave transscleral cyclophotocoagulation (CW-TSCPC) in patients with medically uncontrolled secondary glaucoma following pars plana vitrectomy (PPV) and intravitreal silicone oil injection (SOI). Patients and Methods: This retrospective study enrolled patients with medically uncontrolled glaucoma secondary to PPV with SOI who underwent TSCPC using slow coagulation TSCPC settings (power of 1250 milliwatt and duration of 4 s). The primary outcome measure was surgical success at 12 months. Surgical success was defined as an IOP 6-21 mmHg and reduced ≥20% from baseline, no reoperation for glaucoma, and no loss of light-perception vision. Secondary outcome measures included number of glaucoma medications, visual acuity (VA) changes, and surgical complications. Results: A total of 18 eyes of 18 patients were included in the study. The mean age and follow up of the patients were 51.94±14.5 years and 16.3±3.5 months, respectively. The mean IOP decreased from 29.7±9.6 mmHg preoperatively to 14.6±6.5 mmHg at 12 months postoperatively (P<0.001). Glaucoma medications were reduced from 4.2±0.9 at baseline to 1.9±1.3 at 12 months after TSCPC (P<0.001). A non-significant change of logMAR VA was observed at 12 months (P=0.722). The success rate at 12 months was 72.2%. No major complications were reported during the first year of follow-up. Conclusions: Slow coagulation TSCPC has high efficacy and minimal complications when used as an initial glaucoma surgical procedure in patients with SO-induced glaucoma.

Original languageEnglish (US)
JournalJournal of glaucoma
StateAccepted/In press - 2021


  • secondary glaucoma
  • silicone oil-induced glaucoma
  • transscleral cyclophotocoagulation

ASJC Scopus subject areas

  • Ophthalmology


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