Slight Renal Effect of Mercury from Amalgam Fillings

Serife Eti, Richard S Weisman, Robert Hoffman, M. M. Reidenberg

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Abstract: The current study was to answer the question: Is enough mercury absorbed from dental amalgam fillings to produce renal damage? One hundred healthy adults (18–44 years old) filled out health questionnaires and voided urine samples. Urine mercury concentration and N‐acetyl‐β‐glucosaminidase (NAG) were measured. Subjects were grouped into those having amalgam fillings (N=66) and those without (N=34). Median (95% Confidence Interval) urine mercury was 1 (1–2) and 0 (0–0.6) ng/ml (P<0.01) and median urine NAG was 23 (18–27) and 16 (11–18) units (P<0.05) in the two groups respectively. People with mercury amalgam fillings excreted slightly more mercury than people without them, and have a very small increase in urinary NAG excretion that is probably of no clinical significance. This dose of mercury absorbed from amalgam appears to be too little to be a public health hazard for renal injury. 1995 Nordic Pharmacological Society

Original languageEnglish (US)
Pages (from-to)47-49
Number of pages3
JournalPharmacology and Toxicology
Volume76
Issue number1
DOIs
StatePublished - 1995
Externally publishedYes

Fingerprint

Mercury amalgams
Mercury
Kidney
Urine
Dental Amalgam
Health hazards
Public health
Health
Public Health
Pharmacology
Confidence Intervals
Wounds and Injuries

ASJC Scopus subject areas

  • Toxicology
  • Pharmacology
  • Health, Toxicology and Mutagenesis

Cite this

Slight Renal Effect of Mercury from Amalgam Fillings. / Eti, Serife; Weisman, Richard S; Hoffman, Robert; Reidenberg, M. M.

In: Pharmacology and Toxicology, Vol. 76, No. 1, 1995, p. 47-49.

Research output: Contribution to journalArticle

Eti, Serife ; Weisman, Richard S ; Hoffman, Robert ; Reidenberg, M. M. / Slight Renal Effect of Mercury from Amalgam Fillings. In: Pharmacology and Toxicology. 1995 ; Vol. 76, No. 1. pp. 47-49.
@article{2f36281a7b3e4b4f803d8254490a33a5,
title = "Slight Renal Effect of Mercury from Amalgam Fillings",
abstract = "Abstract: The current study was to answer the question: Is enough mercury absorbed from dental amalgam fillings to produce renal damage? One hundred healthy adults (18–44 years old) filled out health questionnaires and voided urine samples. Urine mercury concentration and N‐acetyl‐β‐glucosaminidase (NAG) were measured. Subjects were grouped into those having amalgam fillings (N=66) and those without (N=34). Median (95{\%} Confidence Interval) urine mercury was 1 (1–2) and 0 (0–0.6) ng/ml (P<0.01) and median urine NAG was 23 (18–27) and 16 (11–18) units (P<0.05) in the two groups respectively. People with mercury amalgam fillings excreted slightly more mercury than people without them, and have a very small increase in urinary NAG excretion that is probably of no clinical significance. This dose of mercury absorbed from amalgam appears to be too little to be a public health hazard for renal injury. 1995 Nordic Pharmacological Society",
author = "Serife Eti and Weisman, {Richard S} and Robert Hoffman and Reidenberg, {M. M.}",
year = "1995",
doi = "10.1111/j.1600-0773.1995.tb00101.x",
language = "English (US)",
volume = "76",
pages = "47--49",
journal = "Basic and Clinical Pharmacology and Toxicology",
issn = "1742-7835",
publisher = "Wiley-Blackwell",
number = "1",

}

TY - JOUR

T1 - Slight Renal Effect of Mercury from Amalgam Fillings

AU - Eti, Serife

AU - Weisman, Richard S

AU - Hoffman, Robert

AU - Reidenberg, M. M.

PY - 1995

Y1 - 1995

N2 - Abstract: The current study was to answer the question: Is enough mercury absorbed from dental amalgam fillings to produce renal damage? One hundred healthy adults (18–44 years old) filled out health questionnaires and voided urine samples. Urine mercury concentration and N‐acetyl‐β‐glucosaminidase (NAG) were measured. Subjects were grouped into those having amalgam fillings (N=66) and those without (N=34). Median (95% Confidence Interval) urine mercury was 1 (1–2) and 0 (0–0.6) ng/ml (P<0.01) and median urine NAG was 23 (18–27) and 16 (11–18) units (P<0.05) in the two groups respectively. People with mercury amalgam fillings excreted slightly more mercury than people without them, and have a very small increase in urinary NAG excretion that is probably of no clinical significance. This dose of mercury absorbed from amalgam appears to be too little to be a public health hazard for renal injury. 1995 Nordic Pharmacological Society

AB - Abstract: The current study was to answer the question: Is enough mercury absorbed from dental amalgam fillings to produce renal damage? One hundred healthy adults (18–44 years old) filled out health questionnaires and voided urine samples. Urine mercury concentration and N‐acetyl‐β‐glucosaminidase (NAG) were measured. Subjects were grouped into those having amalgam fillings (N=66) and those without (N=34). Median (95% Confidence Interval) urine mercury was 1 (1–2) and 0 (0–0.6) ng/ml (P<0.01) and median urine NAG was 23 (18–27) and 16 (11–18) units (P<0.05) in the two groups respectively. People with mercury amalgam fillings excreted slightly more mercury than people without them, and have a very small increase in urinary NAG excretion that is probably of no clinical significance. This dose of mercury absorbed from amalgam appears to be too little to be a public health hazard for renal injury. 1995 Nordic Pharmacological Society

UR - http://www.scopus.com/inward/record.url?scp=0028895946&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028895946&partnerID=8YFLogxK

U2 - 10.1111/j.1600-0773.1995.tb00101.x

DO - 10.1111/j.1600-0773.1995.tb00101.x

M3 - Article

C2 - 7753757

AN - SCOPUS:0028895946

VL - 76

SP - 47

EP - 49

JO - Basic and Clinical Pharmacology and Toxicology

JF - Basic and Clinical Pharmacology and Toxicology

SN - 1742-7835

IS - 1

ER -