Skin Diseases in Children with HIV Infection and Their Association with Degree of Immunosuppression

Wilma Lim, Neil Sadick, Anil Gupta, Mark Kaplan, Savita Pahwa

Research output: Contribution to journalArticlepeer-review

38 Scopus citations

Abstract

Since the recognition of the acquired immunodeficiency syndrome (AIDS) in 1981, several dermatologic manifestations have been associated with the syndrome, including candidiasis, dermatophyte infection, molluscum contagiosum, herpes simplex and zoster, bacterial infection, and malignancy. Skin diseases have been observed in both the adult and the pediatric human immunodeficiency virus (HIV) infection in an academic hospital setting in relationship to the current CDC classification of pediatric HIV infection. The severity of dermatologic manifestations is correlated with the immune status of the patients. The latter was determined by T4 helper cell numbers and lymphoproliferative responses to mitogens and recall antigens. More severe T helper cell depletion was associated with a wider spectrum and increased severity of dermatologic manifestations.

Original languageEnglish (US)
Pages (from-to)24-30
Number of pages7
JournalInternational journal of dermatology
Volume29
Issue number1
DOIs
StatePublished - Jan 1990
Externally publishedYes

ASJC Scopus subject areas

  • Dermatology

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