Sites of paradoxical action of the LHRH agonist (D-Trp6)-LHRH

A. Arimura, S. Talbot, P. C. Serafini, Andrew V Schally

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Immature intact and hypophysectomized female rats, which were primed with gonadotropin, were injected subcutaneously with 0.9% saline or 0.2 or 2 μg of (D-Trp6)-LHRH once daily for 7 days. Ovarian LH/hCG receptors and ovarian weight were measured 24 hours after the last analog or saline injection. A significant reduction (P < 0.01) of ovarian LH/hCG receptors in both intact and hypophysectomized rats was observed following administration of (D-Trp6)-LHRH may indicate that the analog has a direct effect on the ovaries.

Original languageEnglish
Pages (from-to)151-156
Number of pages6
JournalInternational Journal of Fertility
Volume25
Issue number3
StatePublished - Dec 1 1980
Externally publishedYes

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LH Receptors
Gonadotropin-Releasing Hormone
Gonadotropins
Ovary
Weights and Measures
Injections

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Sites of paradoxical action of the LHRH agonist (D-Trp6)-LHRH. / Arimura, A.; Talbot, S.; Serafini, P. C.; Schally, Andrew V.

In: International Journal of Fertility, Vol. 25, No. 3, 01.12.1980, p. 151-156.

Research output: Contribution to journalArticle

Arimura, A, Talbot, S, Serafini, PC & Schally, AV 1980, 'Sites of paradoxical action of the LHRH agonist (D-Trp6)-LHRH', International Journal of Fertility, vol. 25, no. 3, pp. 151-156.
Arimura, A. ; Talbot, S. ; Serafini, P. C. ; Schally, Andrew V. / Sites of paradoxical action of the LHRH agonist (D-Trp6)-LHRH. In: International Journal of Fertility. 1980 ; Vol. 25, No. 3. pp. 151-156.
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