Abstract
Sirt1, an enzyme that removes acetyl groups from specific nuclear proteins, has been linked to the regulation of aging. It is now clear that Sirt1 also controls hepatic glucose metabolism by serving as a sensor of the metabolic status in hepatocytes.
| Original language | English |
|---|---|
| Pages (from-to) | 34-36 |
| Number of pages | 3 |
| Journal | Nature Medicine |
| Volume | 12 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 1 2006 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)
- Medicine(all)
Cite this
Sirt1 : A metabolic master switch that modulates lifespan. / Leibiger, Ingo B.; Berggren, Per Olof.
In: Nature Medicine, Vol. 12, No. 1, 01.01.2006, p. 34-36.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Sirt1
T2 - A metabolic master switch that modulates lifespan
AU - Leibiger, Ingo B.
AU - Berggren, Per Olof
PY - 2006/1/1
Y1 - 2006/1/1
N2 - Sirt1, an enzyme that removes acetyl groups from specific nuclear proteins, has been linked to the regulation of aging. It is now clear that Sirt1 also controls hepatic glucose metabolism by serving as a sensor of the metabolic status in hepatocytes.
AB - Sirt1, an enzyme that removes acetyl groups from specific nuclear proteins, has been linked to the regulation of aging. It is now clear that Sirt1 also controls hepatic glucose metabolism by serving as a sensor of the metabolic status in hepatocytes.
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U2 - 10.1038/nm0106-34
DO - 10.1038/nm0106-34
M3 - Article
VL - 12
SP - 34
EP - 36
JO - Nature Medicine
JF - Nature Medicine
SN - 1078-8956
IS - 1
ER -