Sirt1: A metabolic master switch that modulates lifespan

Ingo B. Leibiger; Per Olof Berggren

doi:10.1038/nm0106-34

Sirt1: A metabolic master switch that modulates lifespan

Ingo B. Leibiger, Per Olof Berggren

Surgery

Research output: Contribution to journal › Short survey › peer-review

96 Scopus citations

Abstract

Sirt1, an enzyme that removes acetyl groups from specific nuclear proteins, has been linked to the regulation of aging. It is now clear that Sirt1 also controls hepatic glucose metabolism by serving as a sensor of the metabolic status in hepatocytes.

Original language	English (US)
Pages (from-to)	34-36
Number of pages	3
Journal	Nature medicine
Volume	12
Issue number	1
DOIs	https://doi.org/10.1038/nm0106-34
State	Published - Jan 2006

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

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10.1038/nm0106-34

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title = "Sirt1: A metabolic master switch that modulates lifespan",

abstract = "Sirt1, an enzyme that removes acetyl groups from specific nuclear proteins, has been linked to the regulation of aging. It is now clear that Sirt1 also controls hepatic glucose metabolism by serving as a sensor of the metabolic status in hepatocytes.",

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Sirt1: A metabolic master switch that modulates lifespan

Abstract

ASJC Scopus subject areas

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