Sirt1: A metabolic master switch that modulates lifespan

Ingo B. Leibiger, Per Olof Berggren

Research output: Contribution to journalShort survey

92 Scopus citations

Abstract

Sirt1, an enzyme that removes acetyl groups from specific nuclear proteins, has been linked to the regulation of aging. It is now clear that Sirt1 also controls hepatic glucose metabolism by serving as a sensor of the metabolic status in hepatocytes.

Original languageEnglish (US)
Pages (from-to)34-36
Number of pages3
JournalNature medicine
Volume12
Issue number1
DOIs
StatePublished - Jan 1 2006

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Fingerprint Dive into the research topics of 'Sirt1: A metabolic master switch that modulates lifespan'. Together they form a unique fingerprint.

  • Cite this