Sinus histiocytosis with massive lymphadenopathy. A case with unusual skin involvement and a therapeutic response to vinblastine‐loaded platelets

Neal S. Penneys, Yeon S. Ahn, E. Churchill McKinney, Thomas McCleod, Gerald Byrne, John Byrnes, Mehrdad Nadji

Research output: Contribution to journalArticle

26 Scopus citations

Abstract

A patient with sinus histiocytosis with massive lymphadenopathy had unusual skin lesions and progressive internal involvement. Both aspects responded dramatically to the administration of vinblastine-loaded platelets. Vinblastine-loaded, idiopathic thrombocytopenic purpura antibody-coated platelets are a rationale therapy for a disease characterized by the presence of actively phagocytosing histiocytes.

Original languageEnglish (US)
Pages (from-to)1994-1998
Number of pages5
JournalCancer
Volume49
Issue number10
DOIs
StatePublished - May 15 1982

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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