Single superficial versus dual systems venous anastomoses in radial forearm free flap: A meta-analysis

Shuang Bai, Zhong Fei Xu, Wei Yi Duan, Fa Yu Liu, Dong Hui Huang, Chang Fu Sun, Sanjoy Bhattacharya

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Background: The radial forearm free flap (RFFF) has been widely used with increasing frequency in head and neck reconstruction following extirpative surgery. The controversy of the venous anastomoses patterns still exists. Thus, we conducted a meta-analysis to assess the relationship between the venous anastomoses patterns and venous compromise. Methods: MEDLINE, PubMed, Web of Science, and Wanfang databases were searched for studies reporting the different venous anastomoses patterns of the RFFF. A meta-analysis was conducted using the random effects models. Publication bias and sensitivity analysis were also assessed. Results: 6 studies with 992 cases were included in this meta-analysis. The dual anastomosis group tended to have a lower incidence of venous compromise (RR = 1.39). However, the difference was not statistically significant (95%CI: 0.59, 3.24). Conclusions: This meta-analysis indicated that performing dual venous anatomoses consisting of superficial and deep systems conferred a tendency of the reduction with regard to venous compromise.

Original languageEnglish (US)
Article numbere0134805
JournalPloS one
Issue number8
StatePublished - Aug 13 2015

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)
  • General


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