TY - JOUR
T1 - Single-center experience in prostate fiducial marker placement
T2 - Technique and midterm follow-up
AU - Kably, Issam
AU - Bordegaray, Matthew
AU - Shah, Kush
AU - Salsamendi, Jason
AU - Narayanan, Govindarajan
PY - 2014/7
Y1 - 2014/7
N2 - Purpose To describe the technique, technical success, and complications of prostate fiducial marker implantation using transrectal ultrasound (US) guidance in patients undergoing image-guided radiation therapy. Materials and Methods A retrospective review was performed of patients who underwent fiducial marker placement from January 2010-April 2013. In each case, gold markers were placed in the prostate using transrectal US guidance. Computed tomography (CT) was performed after the procedure and evaluated to confirm correct placement. Technical success, complications, and development of symptoms during radiotherapy were reviewed. Results Transrectal US-guided fiducial marker placement was performed on 75 patients (mean age, 62 y; range, 48-79 y) with a mean Gleason score of 7.25 (range, 6-10). Fiducial marker placement was confirmed in the intended location of the prostate or prostate bed for 297 of 300 markers (99%) on follow-up CT imaging. Two markers were placed just outside the prostate capsule, and one marker was lost. Complications included sepsis (n = 1; 1.3%), self-limiting perirectal or intraprostatic hemorrhage (n = 3; 4%), nausea (n = 1; 1.3%), transient hypotension (n = 1; 1.3%), epididymitis (n = 1; 1.3%), and urinary tract infection (n = 1; 1.3%). Complications were seen more frequently in patients with high tumor grade (P =.001) and in patients who developed metastatic disease (P =.01). Conclusions Transrectal US-guided implantation of fiducial markers is technically feasible, is well tolerated, and has a good safety profile.
AB - Purpose To describe the technique, technical success, and complications of prostate fiducial marker implantation using transrectal ultrasound (US) guidance in patients undergoing image-guided radiation therapy. Materials and Methods A retrospective review was performed of patients who underwent fiducial marker placement from January 2010-April 2013. In each case, gold markers were placed in the prostate using transrectal US guidance. Computed tomography (CT) was performed after the procedure and evaluated to confirm correct placement. Technical success, complications, and development of symptoms during radiotherapy were reviewed. Results Transrectal US-guided fiducial marker placement was performed on 75 patients (mean age, 62 y; range, 48-79 y) with a mean Gleason score of 7.25 (range, 6-10). Fiducial marker placement was confirmed in the intended location of the prostate or prostate bed for 297 of 300 markers (99%) on follow-up CT imaging. Two markers were placed just outside the prostate capsule, and one marker was lost. Complications included sepsis (n = 1; 1.3%), self-limiting perirectal or intraprostatic hemorrhage (n = 3; 4%), nausea (n = 1; 1.3%), transient hypotension (n = 1; 1.3%), epididymitis (n = 1; 1.3%), and urinary tract infection (n = 1; 1.3%). Complications were seen more frequently in patients with high tumor grade (P =.001) and in patients who developed metastatic disease (P =.01). Conclusions Transrectal US-guided implantation of fiducial markers is technically feasible, is well tolerated, and has a good safety profile.
UR - http://www.scopus.com/inward/record.url?scp=84903309694&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84903309694&partnerID=8YFLogxK
U2 - 10.1016/j.jvir.2014.03.017
DO - 10.1016/j.jvir.2014.03.017
M3 - Article
C2 - 24788207
AN - SCOPUS:84903309694
VL - 25
SP - 1125-1132.e1
JO - Journal of Vascular and Interventional Radiology
JF - Journal of Vascular and Interventional Radiology
SN - 1051-0443
IS - 7
ER -