Simultaneous Treatment of Petroclival Meningiomas and the Trigeminal Nerve with Gamma Knife Radiosurgery for Tumor-Related Trigeminal Neuralgia

Monica C. Mureb, Yosef Dastazirgada, Carolina Benjamin, John G. Golfinos, Douglas Kondziolka

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

Background: Some petroclival meningiomas cause trigeminal nerve compression, leading to disabling trigeminal neuralgia (TN). Tumor resection and nerve decompression can offer pain relief but might not be feasible in all patients. Simultaneous stereotactic radiosurgery (SRS) to the tumor and nerve is another option. SRS is an effective means of treating meningiomas and TN separately, but data on the efficacy and outcomes of their concomitant treatment are limited. Case Description: We report a series of 4 patients who presented with TN secondary to a petroclival mass causing compression of the trigeminal nerve. All patients underwent SRS to both the petroclival mass and trigeminal nerve in a single session. The average margin tumor dose was 12.25 Gy (range, 12–12.5 Gy), and the average maximum trigeminal nerve dose was 80 Gy (range, 75–85 Gy). In all patients, before intervention, the Barrow Neurologic Institute (BNI) pain intensity score was grade IV or V. At last follow-up (average, 29.8 months), all patients were pain-free (BNI I or IIIA). Two patients experienced reduced facial sensation in 1 or all 3 distributions. No brainstem edema was seen. Conclusions: This series highlights the benefits and safety of simultaneous treatment of petroclival tumors and the trigeminal nerve in a single session for patients affected by tumor-related TN.

Original languageEnglish (US)
Pages (from-to)242-244
Number of pages3
JournalWorld neurosurgery
Volume139
DOIs
StatePublished - Jul 2020
Externally publishedYes

Keywords

  • Gamma knife radiosurgery
  • Petroclival meningioma
  • Stereotactic radiosurgery
  • Trigeminal neuralgia

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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