TY - JOUR
T1 - Simultaneous topography-guided PRK followed by corneal collagen cross-linking for keratoconus
AU - Kymionis, George D.
AU - Kontadakis, Georgios A.
AU - Kounis, George A.
AU - Portaliou, Dimitra M.
AU - Karavitaki, Alexandra E.
AU - Magarakis, Michael
AU - Yoo, Sonia
AU - Pallikaris, Ioannis G.
PY - 2009/9
Y1 - 2009/9
N2 - PURPOSE: To present the results after simultaneous photorefractive keratectomy (PRK) followed by corneal collagen cross-linking (CXL) for progressive keratoconus. METHODS: Twelve patients (14 eyes) with progressive keratoconus were prospectively treated with customized topography-guided PRK with the Pulzar Z1 (wavelength 213 nm, CustomVis) immediately followed by corneal collagen CXL with the use of riboflavin and ultraviolet A irradiation. RESULTS: Mean follow-up was 10.69±5.95 months (range: 3 to 16 months). Mean preoperative spherical equivalent refraction (SE) was -3.03±3.23 diopters (D) and defocus was 4.67±3.29 D; at last follow-up SE and defocus were statistically signifi cantly reduced to -1.29±2.05 D and 3.04±2.53 D, respectively (P<.01). Preoperative mean (logMAR) uncorrected visual acuity was 0.99±0.81 and best spectacle-corrected visual acuity was 0.21±0.19, which improved postoperatively to 0.16±0.15 and 0.11±0.15, respectively. The mean steepest keratometry was reduced from 48.20±3.40 D preoperatively to 45.13±1.80 D at last follow-up. CONCLUSIONS: Simultaneous PRK followed by CXL seems to be a promising treatment capable of offering functional vision in patients with keratoconus.
AB - PURPOSE: To present the results after simultaneous photorefractive keratectomy (PRK) followed by corneal collagen cross-linking (CXL) for progressive keratoconus. METHODS: Twelve patients (14 eyes) with progressive keratoconus were prospectively treated with customized topography-guided PRK with the Pulzar Z1 (wavelength 213 nm, CustomVis) immediately followed by corneal collagen CXL with the use of riboflavin and ultraviolet A irradiation. RESULTS: Mean follow-up was 10.69±5.95 months (range: 3 to 16 months). Mean preoperative spherical equivalent refraction (SE) was -3.03±3.23 diopters (D) and defocus was 4.67±3.29 D; at last follow-up SE and defocus were statistically signifi cantly reduced to -1.29±2.05 D and 3.04±2.53 D, respectively (P<.01). Preoperative mean (logMAR) uncorrected visual acuity was 0.99±0.81 and best spectacle-corrected visual acuity was 0.21±0.19, which improved postoperatively to 0.16±0.15 and 0.11±0.15, respectively. The mean steepest keratometry was reduced from 48.20±3.40 D preoperatively to 45.13±1.80 D at last follow-up. CONCLUSIONS: Simultaneous PRK followed by CXL seems to be a promising treatment capable of offering functional vision in patients with keratoconus.
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U2 - 10.3928/1081597X-20090813-09
DO - 10.3928/1081597X-20090813-09
M3 - Article
C2 - 19772256
AN - SCOPUS:73249135170
VL - 25
SP - S807-S811
JO - Journal of Refractive Surgery
JF - Journal of Refractive Surgery
SN - 1081-597X
IS - 9
ER -