Simultaneous real-time imaging of the ocular anterior segment including the ciliary muscle during accommodation

Yilei Shao, Aizhu Tao, Hong Jiang, Meixiao Shen, Jianguang Zhong, Fan Lu, Jianhua Wang

Research output: Contribution to journalArticle

34 Citations (Scopus)

Abstract

We demonstrated a novel approach of imaging the anterior segment including the ciliary muscle using combined and synchronized two spectral domain optical coherence tomography devices (SD-OCT). In one SD-OCT, a Complementary Metal-Oxide-Semiconductor Transistor (CMOS) camera and an alternating reference arm was used to image the anterior segment from the cornea to the lens. Another SD-OCT for imaging the ciliary muscle was equipped with a light source with a center wavelength of 1,310 nm and a bandwidth of 75 nm. Repeated measurements were performed under relaxed and 4.00 D accommodative stimulus states in six eyes from 6 subjects. We also imaged dynamic changes in the anterior segment in one eye during accommodation. The biometry of the anterior segment and the ciliary muscle was obtained. The combined system appeared to be capable to simultaneously real-time image the biometry of the anterior segment, including the ciliary muscle, in vivo during accommodation.

Original languageEnglish
Pages (from-to)466-480
Number of pages15
JournalBiomedical Optics Express
Volume4
Issue number3
DOIs
StatePublished - Mar 12 2013

Fingerprint

accommodation
muscles
Optical Coherence Tomography
Biometry
Muscles
Equipment and Supplies
tomography
Semiconductors
cornea
Cornea
Oxides
Lenses
Arm
Metals
stimuli
CMOS
light sources
Light
transistors
cameras

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Biotechnology

Cite this

Simultaneous real-time imaging of the ocular anterior segment including the ciliary muscle during accommodation. / Shao, Yilei; Tao, Aizhu; Jiang, Hong; Shen, Meixiao; Zhong, Jianguang; Lu, Fan; Wang, Jianhua.

In: Biomedical Optics Express, Vol. 4, No. 3, 12.03.2013, p. 466-480.

Research output: Contribution to journalArticle

Shao, Yilei ; Tao, Aizhu ; Jiang, Hong ; Shen, Meixiao ; Zhong, Jianguang ; Lu, Fan ; Wang, Jianhua. / Simultaneous real-time imaging of the ocular anterior segment including the ciliary muscle during accommodation. In: Biomedical Optics Express. 2013 ; Vol. 4, No. 3. pp. 466-480.
@article{3ad595cb9a534b458802b67ed33116c8,
title = "Simultaneous real-time imaging of the ocular anterior segment including the ciliary muscle during accommodation",
abstract = "We demonstrated a novel approach of imaging the anterior segment including the ciliary muscle using combined and synchronized two spectral domain optical coherence tomography devices (SD-OCT). In one SD-OCT, a Complementary Metal-Oxide-Semiconductor Transistor (CMOS) camera and an alternating reference arm was used to image the anterior segment from the cornea to the lens. Another SD-OCT for imaging the ciliary muscle was equipped with a light source with a center wavelength of 1,310 nm and a bandwidth of 75 nm. Repeated measurements were performed under relaxed and 4.00 D accommodative stimulus states in six eyes from 6 subjects. We also imaged dynamic changes in the anterior segment in one eye during accommodation. The biometry of the anterior segment and the ciliary muscle was obtained. The combined system appeared to be capable to simultaneously real-time image the biometry of the anterior segment, including the ciliary muscle, in vivo during accommodation.",
author = "Yilei Shao and Aizhu Tao and Hong Jiang and Meixiao Shen and Jianguang Zhong and Fan Lu and Jianhua Wang",
year = "2013",
month = "3",
day = "12",
doi = "10.1364/BOE.4.000466",
language = "English",
volume = "4",
pages = "466--480",
journal = "Biomedical Optics Express",
issn = "2156-7085",
publisher = "The Optical Society",
number = "3",

}

TY - JOUR

T1 - Simultaneous real-time imaging of the ocular anterior segment including the ciliary muscle during accommodation

AU - Shao, Yilei

AU - Tao, Aizhu

AU - Jiang, Hong

AU - Shen, Meixiao

AU - Zhong, Jianguang

AU - Lu, Fan

AU - Wang, Jianhua

PY - 2013/3/12

Y1 - 2013/3/12

N2 - We demonstrated a novel approach of imaging the anterior segment including the ciliary muscle using combined and synchronized two spectral domain optical coherence tomography devices (SD-OCT). In one SD-OCT, a Complementary Metal-Oxide-Semiconductor Transistor (CMOS) camera and an alternating reference arm was used to image the anterior segment from the cornea to the lens. Another SD-OCT for imaging the ciliary muscle was equipped with a light source with a center wavelength of 1,310 nm and a bandwidth of 75 nm. Repeated measurements were performed under relaxed and 4.00 D accommodative stimulus states in six eyes from 6 subjects. We also imaged dynamic changes in the anterior segment in one eye during accommodation. The biometry of the anterior segment and the ciliary muscle was obtained. The combined system appeared to be capable to simultaneously real-time image the biometry of the anterior segment, including the ciliary muscle, in vivo during accommodation.

AB - We demonstrated a novel approach of imaging the anterior segment including the ciliary muscle using combined and synchronized two spectral domain optical coherence tomography devices (SD-OCT). In one SD-OCT, a Complementary Metal-Oxide-Semiconductor Transistor (CMOS) camera and an alternating reference arm was used to image the anterior segment from the cornea to the lens. Another SD-OCT for imaging the ciliary muscle was equipped with a light source with a center wavelength of 1,310 nm and a bandwidth of 75 nm. Repeated measurements were performed under relaxed and 4.00 D accommodative stimulus states in six eyes from 6 subjects. We also imaged dynamic changes in the anterior segment in one eye during accommodation. The biometry of the anterior segment and the ciliary muscle was obtained. The combined system appeared to be capable to simultaneously real-time image the biometry of the anterior segment, including the ciliary muscle, in vivo during accommodation.

UR - http://www.scopus.com/inward/record.url?scp=84874693926&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84874693926&partnerID=8YFLogxK

U2 - 10.1364/BOE.4.000466

DO - 10.1364/BOE.4.000466

M3 - Article

C2 - 23504546

AN - SCOPUS:84874693926

VL - 4

SP - 466

EP - 480

JO - Biomedical Optics Express

JF - Biomedical Optics Express

SN - 2156-7085

IS - 3

ER -