Simultaneous infections with human T cell leukemia virus type I and the human immunodeficiency virus

S. B. Kanner, E. S. Parks, Gwendolyn B Scott, W. P. Parks

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Abstract

Four adults from four separate households were found to have simultaneous retroviral infections with human T cell leukemia virus type I (HTLV-I) and human immunodeficiency virus (HIV). These individuals were seropositive for the HTLV-I env transmembrane protein p21E, and all had antibodies to the HTLV-I core polypeptide p24. All four patients also had antibodies to the HIV env transmembrane polypeptide p41E and to the HIV core polypeptide p24. HTLV-I was isolated from peripheral blood lymphocytes of all four individuals, and both viruses were isolated from two of them. Evidence of HIV transmission was noted in the family contacts. Eight of 10 children of these four adults were seropositive for HIV, presumably because of perinatal transmission from infected mothers. Two of five spouses of these adults were examined; these spouses had antibodies to HIV and were positive for virus. No evidence of HTLV-I transmission was noted in these families.

Original languageEnglish
Pages (from-to)617-625
Number of pages9
JournalJournal of Infectious Diseases
Volume155
Issue number4
StatePublished - Jan 1 1987

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Human T-lymphotropic virus 1
HIV
Infection
Spouses
Peptides
HTLV-I Antibodies
env Gene Products
Viruses
Antibodies
Mothers
Lymphocytes

ASJC Scopus subject areas

  • Immunology
  • Public Health, Environmental and Occupational Health

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Simultaneous infections with human T cell leukemia virus type I and the human immunodeficiency virus. / Kanner, S. B.; Parks, E. S.; Scott, Gwendolyn B; Parks, W. P.

In: Journal of Infectious Diseases, Vol. 155, No. 4, 01.01.1987, p. 617-625.

Research output: Contribution to journalArticle

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