Simultaneous and Interleaved Multinuclear Chemical-Shift Imaging, a Method for Concurrent, Localized Spectroscopy

O. Gonen, J. Murphyboesch, R. Srinivasan, J. N. Hu, H. Jiang, Radka Stoyanova, T. R. Brown

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

A method is proposed for carrying out chemical-shift imaging simultaneously on several nuclei (1H and 31P in this example), using a commercial clinical NMR imager fitted with a second RF channel and a dual-tuned birdcage coil to fit the human head. Nuclei of different γ are examined at the same field of view by exciting each nucleus successively at times proportional to γ during the same phase-encoding gradient waveform. Thus, each higher-γ nucleus is exposed to a smaller area of the gradient. Additionally, since in vivo protons typically have a shorter T1 and roughly an order of magnitude higher sensitivity than phosphorus, it is possible to interleave 1H-only acquisitions between the simultaneous 1H, 31P observations while the lower-γ nucleus relaxes. Consequently, additional information is obtained with either higher spatial resolution or greater sensitivity (more signal averaging) without lengthening the duration of the examination.

Original languageEnglish
Pages (from-to)26-33
Number of pages8
JournalJournal of Magnetic Resonance, Series B
Volume104
Issue number1
DOIs
StatePublished - May 1 1994
Externally publishedYes

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Image sensors
Phosphorus
Protons
Nuclear magnetic resonance
Spectroscopy
Magnetic Resonance Imaging

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Simultaneous and Interleaved Multinuclear Chemical-Shift Imaging, a Method for Concurrent, Localized Spectroscopy. / Gonen, O.; Murphyboesch, J.; Srinivasan, R.; Hu, J. N.; Jiang, H.; Stoyanova, Radka; Brown, T. R.

In: Journal of Magnetic Resonance, Series B, Vol. 104, No. 1, 01.05.1994, p. 26-33.

Research output: Contribution to journalArticle

Gonen, O. ; Murphyboesch, J. ; Srinivasan, R. ; Hu, J. N. ; Jiang, H. ; Stoyanova, Radka ; Brown, T. R. / Simultaneous and Interleaved Multinuclear Chemical-Shift Imaging, a Method for Concurrent, Localized Spectroscopy. In: Journal of Magnetic Resonance, Series B. 1994 ; Vol. 104, No. 1. pp. 26-33.
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