Simple acute appendicitis versus non-perforated gangrenous appendicitis: Is there a difference in the rate of post-operative infectious complications?

Andrea Romano, Punam Parikh, Patricia M Byers, Nicholas Namias

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Background: According to the 2002 Surgical Infection Society Guidelines on Antimicrobial Therapy for Intra-abdominal Infections, antimicrobial therapy is not recommended beyond 24 hours for the treatment of postoperative acute or gangrenous appendicitis without perforation. However, clinicians commonly consider gangrenous appendicitis to pose a greater risk of post-operative infectious complications, such as surgical site infections and intra-abdominal abscesses. This study examines the relative risk of post-operative infection between patients with simple and gangrenous appendicitis.

Methods: A retrospective review of patients with either non-perforated gangrenous or simple appendicitis from 2010 to 2012 was performed at a large urban teaching hospital.

Results: The rate of post-operative intra-abdominal abscess formation, which was diagnosed on patient readmission to the hospital, was significantly greater in patients with non-perforated gangrenous appendicitis in comparison to those with simple non-perforated appendicitis. Also, patients with non-perforated gangrenous appendicitis received extended courses of post-operative antibiotics, despite SIS recommendations.

Conclusions: The role of peri-operative antibiotics for non-perforated gangrenous appendicitis merits further study.

Original languageEnglish
Pages (from-to)517-520
Number of pages4
JournalSurgical Infections
Volume15
Issue number5
DOIs
StatePublished - Jan 1 2014

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Appendicitis
Abdominal Abscess
Anti-Bacterial Agents
Intraabdominal Infections
Surgical Wound Infection
Patient Readmission
Urban Hospitals
Teaching Hospitals
Therapeutics
Guidelines
Infection

ASJC Scopus subject areas

  • Surgery
  • Infectious Diseases
  • Microbiology (medical)

Cite this

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title = "Simple acute appendicitis versus non-perforated gangrenous appendicitis: Is there a difference in the rate of post-operative infectious complications?",
abstract = "Background: According to the 2002 Surgical Infection Society Guidelines on Antimicrobial Therapy for Intra-abdominal Infections, antimicrobial therapy is not recommended beyond 24 hours for the treatment of postoperative acute or gangrenous appendicitis without perforation. However, clinicians commonly consider gangrenous appendicitis to pose a greater risk of post-operative infectious complications, such as surgical site infections and intra-abdominal abscesses. This study examines the relative risk of post-operative infection between patients with simple and gangrenous appendicitis.Methods: A retrospective review of patients with either non-perforated gangrenous or simple appendicitis from 2010 to 2012 was performed at a large urban teaching hospital.Results: The rate of post-operative intra-abdominal abscess formation, which was diagnosed on patient readmission to the hospital, was significantly greater in patients with non-perforated gangrenous appendicitis in comparison to those with simple non-perforated appendicitis. Also, patients with non-perforated gangrenous appendicitis received extended courses of post-operative antibiotics, despite SIS recommendations.Conclusions: The role of peri-operative antibiotics for non-perforated gangrenous appendicitis merits further study.",
author = "Andrea Romano and Punam Parikh and Byers, {Patricia M} and Nicholas Namias",
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AU - Namias, Nicholas

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AB - Background: According to the 2002 Surgical Infection Society Guidelines on Antimicrobial Therapy for Intra-abdominal Infections, antimicrobial therapy is not recommended beyond 24 hours for the treatment of postoperative acute or gangrenous appendicitis without perforation. However, clinicians commonly consider gangrenous appendicitis to pose a greater risk of post-operative infectious complications, such as surgical site infections and intra-abdominal abscesses. This study examines the relative risk of post-operative infection between patients with simple and gangrenous appendicitis.Methods: A retrospective review of patients with either non-perforated gangrenous or simple appendicitis from 2010 to 2012 was performed at a large urban teaching hospital.Results: The rate of post-operative intra-abdominal abscess formation, which was diagnosed on patient readmission to the hospital, was significantly greater in patients with non-perforated gangrenous appendicitis in comparison to those with simple non-perforated appendicitis. Also, patients with non-perforated gangrenous appendicitis received extended courses of post-operative antibiotics, despite SIS recommendations.Conclusions: The role of peri-operative antibiotics for non-perforated gangrenous appendicitis merits further study.

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