Significance of positive semen culture in relation to male infertility and the assisted reproductive technology process

Joshua S. Jue, Ranjith Ramasamy

Research output: Contribution to journalReview article

2 Scopus citations

Abstract

There are currently no WHO guidelines on the indications for semen culture; however, semen cultures are performed in the evaluation of male infertility and the assisted reproductive technology (ART) process. The relevance and significance of positive semen cultures is widely debated in the literature, with no current consensus on the usefulness of this test in relation to male infertility. We review the pathogenic mechanisms of potentially pathogenic bacteria, general bacteria, urethral flora, and skin flora on sperm parameters. We also present, possible routes of semen contamination, measures to reduce contamination, and the clinical significance of culture contamination. First, it is critical to distinguish round cells in semen as leukocytes from immature germ cells. Second, it is critical to distinguish leukocytospermia from infected semen in order to guide management.

Original languageEnglish (US)
Pages (from-to)916-922
Number of pages7
JournalTranslational Andrology and Urology
Volume6
Issue number5
DOIs
StatePublished - Oct 1 2017

Keywords

  • Assisted reproductive technology (ART)
  • Bacteriospermia
  • In vitro fertilization (IVF)
  • Leukocytospermia
  • Male infertility
  • Semen culture

ASJC Scopus subject areas

  • Reproductive Medicine
  • Urology

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