Side effects associated with intravesical mitomycin C

I. Nissenkorn, H. Herrod, M. S. Soloway

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

The nature and severity of side effects accompanying intravesical chemotherapy with mitomycon C were studied in 29 patients. No patient experienced systemic toxicity. Local side effects developed in 7 patients (24 per cent), and consisted of moderate cystitis in 3 and drug-related palmar desquamation, with or without generalized rash, in 4. Based on skin tests 3 of these patients were believed to have a contact dermatitis. The fourth patient had a generalized rash, in addition to palmar desquamation, that appeared after subsequent instillations of mitomycin C and the drug had to be discontinued. Careful cleansing of the hands and perineum on the day of treatment can prevent most skin reactions.

Original languageEnglish
Pages (from-to)596-597
Number of pages2
JournalJournal of Urology
Volume126
Issue number5
StatePublished - Dec 1 1981
Externally publishedYes

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Mitomycin
Exanthema
Perineum
Cystitis
Contact Dermatitis
Skin Tests
Pharmaceutical Preparations
Hand
Drug Therapy
Skin

ASJC Scopus subject areas

  • Urology

Cite this

Nissenkorn, I., Herrod, H., & Soloway, M. S. (1981). Side effects associated with intravesical mitomycin C. Journal of Urology, 126(5), 596-597.

Side effects associated with intravesical mitomycin C. / Nissenkorn, I.; Herrod, H.; Soloway, M. S.

In: Journal of Urology, Vol. 126, No. 5, 01.12.1981, p. 596-597.

Research output: Contribution to journalArticle

Nissenkorn, I, Herrod, H & Soloway, MS 1981, 'Side effects associated with intravesical mitomycin C', Journal of Urology, vol. 126, no. 5, pp. 596-597.
Nissenkorn I, Herrod H, Soloway MS. Side effects associated with intravesical mitomycin C. Journal of Urology. 1981 Dec 1;126(5):596-597.
Nissenkorn, I. ; Herrod, H. ; Soloway, M. S. / Side effects associated with intravesical mitomycin C. In: Journal of Urology. 1981 ; Vol. 126, No. 5. pp. 596-597.
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