Sexual relationships outside primary partnerships and abstinence are associated with lower adherence and adherence gaps: Data from the partners PrEP ancillary adherence study

The Partners Ancillary Adherence Study Team

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Objective: To assess the role of sexual relationships on levels and patterns of adherence to medication for pre-exposure prophylaxis against HIV. Methods: We enrolled 1147 HIV-negative individuals in long-term serodiscordant relationships at 3 sites in Uganda from the Partners Pre-exposure Prophylaxis Study, a randomized placebo-controlled trial of daily oral tenofovir and emtricitabine/tenofovir. We used generalized estimation equations to assess the effects of sexual relationships on low adherence (

Original languageEnglish (US)
Pages (from-to)36-43
Number of pages8
JournalJournal of Acquired Immune Deficiency Syndromes
Volume69
Issue number1
DOIs
StatePublished - May 1 2015
Externally publishedYes

Fingerprint

Tenofovir
HIV
Uganda
Medication Adherence
Randomized Controlled Trials
Placebos
Pre-Exposure Prophylaxis

Keywords

  • adherence
  • Pre-exposure prophylaxis
  • sexual behavior

ASJC Scopus subject areas

  • Infectious Diseases
  • Pharmacology (medical)

Cite this

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title = "Sexual relationships outside primary partnerships and abstinence are associated with lower adherence and adherence gaps: Data from the partners PrEP ancillary adherence study",
abstract = "Objective: To assess the role of sexual relationships on levels and patterns of adherence to medication for pre-exposure prophylaxis against HIV. Methods: We enrolled 1147 HIV-negative individuals in long-term serodiscordant relationships at 3 sites in Uganda from the Partners Pre-exposure Prophylaxis Study, a randomized placebo-controlled trial of daily oral tenofovir and emtricitabine/tenofovir. We used generalized estimation equations to assess the effects of sexual relationships on low adherence (",
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author = "{The Partners Ancillary Adherence Study Team} and Alexander Kintu and Hankinson, {Susan E.} and Raji Balasubramanian and Karen Ertel and Elioda Tumwesigye and Bangsberg, {David R.} and Haberer, {Jessica E.} and Steven Safren and Christina Psaros and Norma Ware and Monique Wyatt and Connie Celum and Baeten, {Jared M.} and Deborah Donnell and Craig Hendrix and Stephen Asiimwe and Elly Katabira and Allan Rolland and Edith Nakku-Joloba and James Campbell and Aloysious Kakia",
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pages = "36--43",
journal = "Journal of acquired immune deficiency syndromes (1999)",
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TY - JOUR

T1 - Sexual relationships outside primary partnerships and abstinence are associated with lower adherence and adherence gaps

T2 - Data from the partners PrEP ancillary adherence study

AU - The Partners Ancillary Adherence Study Team

AU - Kintu, Alexander

AU - Hankinson, Susan E.

AU - Balasubramanian, Raji

AU - Ertel, Karen

AU - Tumwesigye, Elioda

AU - Bangsberg, David R.

AU - Haberer, Jessica E.

AU - Safren, Steven

AU - Psaros, Christina

AU - Ware, Norma

AU - Wyatt, Monique

AU - Celum, Connie

AU - Baeten, Jared M.

AU - Donnell, Deborah

AU - Hendrix, Craig

AU - Asiimwe, Stephen

AU - Katabira, Elly

AU - Rolland, Allan

AU - Nakku-Joloba, Edith

AU - Campbell, James

AU - Kakia, Aloysious

PY - 2015/5/1

Y1 - 2015/5/1

N2 - Objective: To assess the role of sexual relationships on levels and patterns of adherence to medication for pre-exposure prophylaxis against HIV. Methods: We enrolled 1147 HIV-negative individuals in long-term serodiscordant relationships at 3 sites in Uganda from the Partners Pre-exposure Prophylaxis Study, a randomized placebo-controlled trial of daily oral tenofovir and emtricitabine/tenofovir. We used generalized estimation equations to assess the effects of sexual relationships on low adherence (

AB - Objective: To assess the role of sexual relationships on levels and patterns of adherence to medication for pre-exposure prophylaxis against HIV. Methods: We enrolled 1147 HIV-negative individuals in long-term serodiscordant relationships at 3 sites in Uganda from the Partners Pre-exposure Prophylaxis Study, a randomized placebo-controlled trial of daily oral tenofovir and emtricitabine/tenofovir. We used generalized estimation equations to assess the effects of sexual relationships on low adherence (

KW - adherence

KW - Pre-exposure prophylaxis

KW - sexual behavior

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JO - Journal of acquired immune deficiency syndromes (1999)

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