Severity of symptoms in chronically institutionalized geriatric schizophrenic patients

M. Davidson, Philip D Harvey, P. Powchik, M. Parrella, L. White, H. Y. Knobler, M. F. Losonczy, R. S E Keefe, S. Katz, E. Frecska

Research output: Contribution to journalArticle

265 Citations (Scopus)

Abstract

Objective: The goal of this study was to characterize the symptoms of geriatric, chronically ill, institutionalized schizophrenic patients and investigate age-related differences in schizophrenic symptoms and cognitive performance from early adulthood to late senescence. Method: The Positive and Negative Syndrome Scale and the Mini-Mental State examination were used to assess the schizophrenic symptoms and cognitive performance, respectively, of 393 institutionalized schizophrenic patients stratified into seven groups designated by 10-year age intervals from 25 years to over 85 years. Results: In the comparisons of the seven age groups, significant differences between groups in positive and negative subscale scores on the Positive and Negative Syndrome Scale and in Mini-Mental State scores were revealed. Significant correlations between Mini-Mental State scores and Positive and Negative Syndrome Scale negative symptom scores, but not positive symptom scores, were found for all age groups, except for the youngest patients studied. Current treatment with neuroleptics and prior treatment with ECT, insulin coma, or leukotomy could not account for the poor cognitive performance of the older schizophrenic patients. Conclusions: The older schizophrenic patients continued to experience psychotic and nonpsychotic symptoms in senescence. Their positive symptoms were moderately less severe and their negative symptoms and cognitive impairment were significantly more severe than those of the younger patients. Somatic treatment appeared not to be responsible for the severe cognitive impairment and negative symptoms of the older patients. These data are relevant to chronically hospitalized geriatric schizophrenic patients but not necessarily to all geriatric schizophrenic patients.

Original languageEnglish
Pages (from-to)197-207
Number of pages11
JournalAmerican Journal of Psychiatry
Volume152
Issue number2
StatePublished - Jan 1 1995
Externally publishedYes

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Geriatrics
Neurobehavioral Manifestations
Insulin Coma
Age Groups
Psychosurgery
Antipsychotic Agents
Chronic Disease
Therapeutics

ASJC Scopus subject areas

  • Psychiatry and Mental health

Cite this

Davidson, M., Harvey, P. D., Powchik, P., Parrella, M., White, L., Knobler, H. Y., ... Frecska, E. (1995). Severity of symptoms in chronically institutionalized geriatric schizophrenic patients. American Journal of Psychiatry, 152(2), 197-207.

Severity of symptoms in chronically institutionalized geriatric schizophrenic patients. / Davidson, M.; Harvey, Philip D; Powchik, P.; Parrella, M.; White, L.; Knobler, H. Y.; Losonczy, M. F.; Keefe, R. S E; Katz, S.; Frecska, E.

In: American Journal of Psychiatry, Vol. 152, No. 2, 01.01.1995, p. 197-207.

Research output: Contribution to journalArticle

Davidson, M, Harvey, PD, Powchik, P, Parrella, M, White, L, Knobler, HY, Losonczy, MF, Keefe, RSE, Katz, S & Frecska, E 1995, 'Severity of symptoms in chronically institutionalized geriatric schizophrenic patients', American Journal of Psychiatry, vol. 152, no. 2, pp. 197-207.
Davidson M, Harvey PD, Powchik P, Parrella M, White L, Knobler HY et al. Severity of symptoms in chronically institutionalized geriatric schizophrenic patients. American Journal of Psychiatry. 1995 Jan 1;152(2):197-207.
Davidson, M. ; Harvey, Philip D ; Powchik, P. ; Parrella, M. ; White, L. ; Knobler, H. Y. ; Losonczy, M. F. ; Keefe, R. S E ; Katz, S. ; Frecska, E. / Severity of symptoms in chronically institutionalized geriatric schizophrenic patients. In: American Journal of Psychiatry. 1995 ; Vol. 152, No. 2. pp. 197-207.
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