Seroprevalence of Helicobacter pylori Infection in a National Cohort of Veterans With Noncardia Gastric Adenocarcinoma

Shria Kumar, David C. Metz, David E. Kaplan, David S. Goldberg

Research output: Contribution to journalShort surveypeer-review

4 Scopus citations

Abstract

Conventional teaching is that Helicobacter pylori infection is required for the development of non-cardia gastric adenocarcinoma (NCGC) through a sequence of atrophic gastritis, intestinal metaplasia, dysplasia, and finally, cancer.1–3 However, studies have not demonstrated a 100% rate of H pylori infection in gastric malignancy, hypothesized to be due to false negatives, gastric atrophy leading to apparent loss of infection, and inclusion of cardia, nonintestinal cancers.1–3

Original languageEnglish (US)
Pages (from-to)1235-1237.e1
JournalClinical Gastroenterology and Hepatology
Volume18
Issue number5
DOIs
StatePublished - May 2020
Externally publishedYes

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

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