Serologic diagnosis of active toxoplasmosis complicating malignant diseases. Usefulness of IgM antibodies and gel‐diffusion

Milford N. Lunde, Albert H. Gelderman, Sherrard L. Hayes, Charles L. Vogel

Research output: Contribution to journalArticle

17 Scopus citations

Abstract

The indirect fluorescent antibody test for antitoxoplasma IgM antibodies and Ouchterlony gel‐diffusion were used in conjunction with the dye test, hemag‐glutination, and complement‐fixation tests to examine the serologic characteristics of 3 patients with suspected active toxoplasmosis complicating leukemia. Serum titers from 10 additional patients without apparent clinical evidence of toxoplasmosis but having positive dye and hemagglutination tests were also studied. Results suggest that the presence of IgM antibodies and precipitin lines in agar gel may be useful indicators of active toxoplasmosis in patients with malignant disease.

Original languageEnglish (US)
Pages (from-to)637-643
Number of pages7
JournalCancer
Volume25
Issue number3
DOIs
StatePublished - Mar 1970
Externally publishedYes

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ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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