Sentinel node biopsy for squamous cell carcinoma of the head and neck

Francisco Civantos, Robert Zitsch, Anthony Bared, Ayman Amin

Research output: Contribution to journalReview articlepeer-review

50 Scopus citations


The clinical utility of sentinel node biopsy for melanoma has led multiple investigators to apply this approach to other cutaneous malignancies as well as to early cancers of the upper aerodigestive tract. Data are most extensive for oral cancer. A multi-institutional pathologic validation trial for selected oral cancers provided negative predictive values of 96%. Subsequent trials should document clinical follow-up. This technique may ultimately play a wider role in the management of mucosal cancers.

Original languageEnglish (US)
Pages (from-to)683-690
Number of pages8
JournalJournal of surgical oncology
Issue number8
StatePublished - Jun 15 2008


  • ACOSOG Z0360 validation trial
  • Lymphatic basin
  • Mucosal squamous cell carcinoma

ASJC Scopus subject areas

  • Surgery
  • Oncology


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