Sentinel lymph node biopsy in head and neck cancer

Ivan H. El-Sayed, Mark I. Singer, Frank Civantos

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


Despite concerns of anatomic complexity, SLNB seems to be safe and effective for CMM in the head and neck. The prognostic information is valuable to the patient and provides a staging tool for the physician. Although the role of neck dissection is controversial, evidence suggests that a subset of patients benefit from ELND. Because the only proven cure for CMM is surgical resection, identification of subgroups that are amenable to lymphadenectomy may improve their survival. Data provided by SLNB raise questions about the studies on ELND that did not benefit from the information provided by a SLNB. SLNB has promise for providing important information in other cancers of the head and neck such as Merkel cell cancer or oral squamous cell cancer, but further research is needed.

Original languageEnglish (US)
Pages (from-to)145-160
Number of pages16
JournalOtolaryngologic Clinics of North America
Issue number1
StatePublished - Feb 2005

ASJC Scopus subject areas

  • Otorhinolaryngology


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