Abstract
Despite concerns of anatomic complexity, SLNB seems to be safe and effective for CMM in the head and neck. The prognostic information is valuable to the patient and provides a staging tool for the physician. Although the role of neck dissection is controversial, evidence suggests that a subset of patients benefit from ELND. Because the only proven cure for CMM is surgical resection, identification of subgroups that are amenable to lymphadenectomy may improve their survival. Data provided by SLNB raise questions about the studies on ELND that did not benefit from the information provided by a SLNB. SLNB has promise for providing important information in other cancers of the head and neck such as Merkel cell cancer or oral squamous cell cancer, but further research is needed.
| Original language | English |
|---|---|
| Pages (from-to) | 145-160 |
| Number of pages | 16 |
| Journal | Otolaryngologic Clinics of North America |
| Volume | 38 |
| Issue number | 1 |
| DOIs | |
| State | Published - Feb 1 2005 |
Fingerprint
ASJC Scopus subject areas
- Otorhinolaryngology
Cite this
Sentinel lymph node biopsy in head and neck cancer. / El-Sayed, Ivan H.; Singer, Mark I.; Civantos, Francisco.
In: Otolaryngologic Clinics of North America, Vol. 38, No. 1, 01.02.2005, p. 145-160.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Sentinel lymph node biopsy in head and neck cancer
AU - El-Sayed, Ivan H.
AU - Singer, Mark I.
AU - Civantos, Francisco
PY - 2005/2/1
Y1 - 2005/2/1
N2 - Despite concerns of anatomic complexity, SLNB seems to be safe and effective for CMM in the head and neck. The prognostic information is valuable to the patient and provides a staging tool for the physician. Although the role of neck dissection is controversial, evidence suggests that a subset of patients benefit from ELND. Because the only proven cure for CMM is surgical resection, identification of subgroups that are amenable to lymphadenectomy may improve their survival. Data provided by SLNB raise questions about the studies on ELND that did not benefit from the information provided by a SLNB. SLNB has promise for providing important information in other cancers of the head and neck such as Merkel cell cancer or oral squamous cell cancer, but further research is needed.
AB - Despite concerns of anatomic complexity, SLNB seems to be safe and effective for CMM in the head and neck. The prognostic information is valuable to the patient and provides a staging tool for the physician. Although the role of neck dissection is controversial, evidence suggests that a subset of patients benefit from ELND. Because the only proven cure for CMM is surgical resection, identification of subgroups that are amenable to lymphadenectomy may improve their survival. Data provided by SLNB raise questions about the studies on ELND that did not benefit from the information provided by a SLNB. SLNB has promise for providing important information in other cancers of the head and neck such as Merkel cell cancer or oral squamous cell cancer, but further research is needed.
UR - http://www.scopus.com/inward/record.url?scp=11844277098&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=11844277098&partnerID=8YFLogxK
U2 - 10.1016/j.otc.2004.09.004
DO - 10.1016/j.otc.2004.09.004
M3 - Article
C2 - 15649505
AN - SCOPUS:11844277098
VL - 38
SP - 145
EP - 160
JO - Otolaryngologic Clinics of North America
JF - Otolaryngologic Clinics of North America
SN - 0030-6665
IS - 1
ER -