Semi-supervised classification using sparse representation for cancer recurrence prediction

Yan Cui, Xiaodong Cai, Zhong Jin

Research output: Chapter in Book/Report/Conference proceedingConference contribution

6 Scopus citations

Abstract

Gene expression profiles have been used to predict cancer recurrence or other clinical outcomes of cancer patients. However, clinical information of cancer patients is often incomplete, which yields many unlabeled samples that cannot be used in supervised learning. In this is paper, we develop a novel semi-supervised leaning (SSL) method that uses both labeled and unlabeled patient samples to predict cancer recurrence. Our new SSL algorithm employs a sparse representation approach where a labeled sample is represented as a combination of a small number of properly chosen unlabeled samples. Experiments with a set of gene expression data from patients with colorectal cancer(CRC) demonstrate that our SSL algorithm can improve prediction accuracy compared to other two SSL methods including TSVM and T3VM, and the traditional support vector machine.

Original languageEnglish (US)
Title of host publication2013 IEEE International Workshop on Genomic Signal Processing and Statistics, GENSIPS 2013 - Proceedings
Pages102-105
Number of pages4
DOIs
StatePublished - Dec 1 2013
Event2013 IEEE International Workshop on Genomic Signal Processing and Statistics, GENSIPS 2013 - Houston, TX, United States
Duration: Nov 17 2013Nov 19 2013

Publication series

NameProceedings - IEEE International Workshop on Genomic Signal Processing and Statistics
ISSN (Print)2150-3001
ISSN (Electronic)2150-301X

Other

Other2013 IEEE International Workshop on Genomic Signal Processing and Statistics, GENSIPS 2013
CountryUnited States
CityHouston, TX
Period11/17/1311/19/13

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology (miscellaneous)
  • Computational Theory and Mathematics
  • Signal Processing
  • Biomedical Engineering

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  • Cite this

    Cui, Y., Cai, X., & Jin, Z. (2013). Semi-supervised classification using sparse representation for cancer recurrence prediction. In 2013 IEEE International Workshop on Genomic Signal Processing and Statistics, GENSIPS 2013 - Proceedings (pp. 102-105). [6735949] (Proceedings - IEEE International Workshop on Genomic Signal Processing and Statistics). https://doi.org/10.1109/GENSIPS.2013.6735949