Selection criteria and preoperative investigation of patients with focal epilepsy who lack a localized structural lesion

M. Duchowny, P. Jayakar, S. Koh

Research output: Contribution to journalArticle

17 Scopus citations

Abstract

Children with medically resistant epilepsy are often referred for surgical evaluation. The absence of a specific focal lesion on MRI may render the work-up difficult. In response to the need to localize the primary area of epileptogenesis, surgery protocols are being developed which rely on clinical semiology, EEG and functional imaging data. In selected cases, intracranial EEG monitoring may be required. While testing more often depends on the convergence of modalities, it is possible to localize seizure origin in the majority of children, and fully excise the epileptogenic region. This review presents the etiology and preoperative modalities available for children with intractable, non-lesional epilepsy.

Original languageEnglish (US)
Pages (from-to)219-226
Number of pages8
JournalEpileptic Disorders
Volume2
Issue number4
StatePublished - Dec 1 2000

Keywords

  • Epilepsy surgery
  • Functional neuroimaging
  • Intractable epilepsy
  • Partial seizures

ASJC Scopus subject areas

  • Clinical Neurology

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