Abstract
Children with medically resistant epilepsy are often referred for surgical evaluation. The absence of a specific focal lesion on MRI may render the work-up difficult. In response to the need to localize the primary area of epileptogenesis, surgery protocols are being developed which rely on clinical semiology, EEG and functional imaging data. In selected cases, intracranial EEG monitoring may be required. While testing more often depends on the convergence of modalities, it is possible to localize seizure origin in the majority of children, and fully excise the epileptogenic region. This review presents the etiology and preoperative modalities available for children with intractable, non-lesional epilepsy.
| Original language | English |
|---|---|
| Pages (from-to) | 219-226 |
| Number of pages | 8 |
| Journal | Epileptic Disorders |
| Volume | 2 |
| Issue number | 4 |
| State | Published - Dec 1 2000 |
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Keywords
- Epilepsy surgery
- Functional neuroimaging
- Intractable epilepsy
- Partial seizures
ASJC Scopus subject areas
- Clinical Neurology
Cite this
Selection criteria and preoperative investigation of patients with focal epilepsy who lack a localized structural lesion. / Duchowny, M.; Jayakar, P.; Koh, S.
In: Epileptic Disorders, Vol. 2, No. 4, 01.12.2000, p. 219-226.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Selection criteria and preoperative investigation of patients with focal epilepsy who lack a localized structural lesion
AU - Duchowny, M.
AU - Jayakar, P.
AU - Koh, S.
PY - 2000/12/1
Y1 - 2000/12/1
N2 - Children with medically resistant epilepsy are often referred for surgical evaluation. The absence of a specific focal lesion on MRI may render the work-up difficult. In response to the need to localize the primary area of epileptogenesis, surgery protocols are being developed which rely on clinical semiology, EEG and functional imaging data. In selected cases, intracranial EEG monitoring may be required. While testing more often depends on the convergence of modalities, it is possible to localize seizure origin in the majority of children, and fully excise the epileptogenic region. This review presents the etiology and preoperative modalities available for children with intractable, non-lesional epilepsy.
AB - Children with medically resistant epilepsy are often referred for surgical evaluation. The absence of a specific focal lesion on MRI may render the work-up difficult. In response to the need to localize the primary area of epileptogenesis, surgery protocols are being developed which rely on clinical semiology, EEG and functional imaging data. In selected cases, intracranial EEG monitoring may be required. While testing more often depends on the convergence of modalities, it is possible to localize seizure origin in the majority of children, and fully excise the epileptogenic region. This review presents the etiology and preoperative modalities available for children with intractable, non-lesional epilepsy.
KW - Epilepsy surgery
KW - Functional neuroimaging
KW - Intractable epilepsy
KW - Partial seizures
UR - http://www.scopus.com/inward/record.url?scp=0034487614&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0034487614&partnerID=8YFLogxK
M3 - Article
C2 - 11174153
AN - SCOPUS:0034487614
VL - 2
SP - 219
EP - 226
JO - Epileptic Disorders
JF - Epileptic Disorders
SN - 1294-9361
IS - 4
ER -