Sebaceous cell carcinoma of the eyelid and the human immunodeficiency virus

M. T. Yen, D. T. Tse

Research output: Contribution to journalArticlepeer-review

29 Scopus citations


Purpose: Patients infected with the human immunodeficiency virus (HIV) are at increased risk for developing malignancies, which are acquired at a younger age and are more aggressive. Sebaceous cell carcinoma is a rare eyelid tumor typically occurring in the seventh decade of life. We report two cases of sebaceous cell carcinoma in young HIV-infected patients. Methods: Case series and review of the literature. We describe two HIV-infected patients with sebaceous cell carcinoma of the eyelid and caruncle. The first patient was a 36-year-old woman with a 9-month history of an enlarging right lower eyelid mass. The second patient was a 34-year-old man with a 6-month history of an enlarging right caruncular mass. Results: Biopsy showed both masses to be sebaceous cell carcinoma. The first patient underwent Mohs' micrographic excision of the lesion followed by reconstruction of the full-thickness eyelid defect with a combination of tarsoconjunctival and myocutaneous advancement flaps. The second patient underwent exenteration because of orbital involvement. Conclusion: Sebaceous cell carcinoma should be considered for any suspicious eyelid lesion in young HIV-infected patients.

Original languageEnglish (US)
Pages (from-to)206-210
Number of pages5
JournalOphthalmic plastic and reconstructive surgery
Issue number3
StatePublished - Jan 1 2000

ASJC Scopus subject areas

  • Surgery
  • Ophthalmology


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