Abstract
To determine the role of genetics in bipolar affective disorders it was necessary to have correct diagnosis and large homogenous population(s). To identify a marker linked to the disease two additional factors were important, a correct model for genetic transmission and highly polymorphic DNA markers. With the establishment of a linked marker the aim is to identify the susceptibility gene. Two approaches are the prediction of candidate genes and/or the determination of a physical map of the region.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 569-575 |
| Number of pages | 7 |
| Journal | Journal of Psychiatric Research |
| Volume | 21 |
| Issue number | 4 |
| DOIs | |
| State | Published - 1987 |
ASJC Scopus subject areas
- Psychiatry and Mental health
- Biological Psychiatry
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Cite this
Gerhard, D. S., Egeland, J. A., Pauls, D. L., & Housman, D. E. (1987). Search for a gene that predisposes individuals to BPI disorder. Journal of Psychiatric Research, 21(4), 569-575. https://doi.org/10.1016/0022-3956(87)90106-3