Abstract
To determine the role of genetics in bipolar affective disorders it was necessary to have correct diagnosis and large homogenous population(s). To identify a marker linked to the disease two additional factors were important, a correct model for genetic transmission and highly polymorphic DNA markers. With the establishment of a linked marker the aim is to identify the susceptibility gene. Two approaches are the prediction of candidate genes and/or the determination of a physical map of the region.
| Original language | English |
|---|---|
| Pages (from-to) | 569-575 |
| Number of pages | 7 |
| Journal | Journal of Psychiatric Research |
| Volume | 21 |
| Issue number | 4 |
| DOIs | |
| State | Published - Jan 1 1987 |
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ASJC Scopus subject areas
- Psychiatry and Mental health
- Biological Psychiatry
- Psychology(all)
Cite this
Search for a gene that predisposes individuals to BPI disorder. / Gerhard, Daniela S.; Egeland, Janice; Pauls, David L.; Housman, David E.
In: Journal of Psychiatric Research, Vol. 21, No. 4, 01.01.1987, p. 569-575.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Search for a gene that predisposes individuals to BPI disorder
AU - Gerhard, Daniela S.
AU - Egeland, Janice
AU - Pauls, David L.
AU - Housman, David E.
PY - 1987/1/1
Y1 - 1987/1/1
N2 - To determine the role of genetics in bipolar affective disorders it was necessary to have correct diagnosis and large homogenous population(s). To identify a marker linked to the disease two additional factors were important, a correct model for genetic transmission and highly polymorphic DNA markers. With the establishment of a linked marker the aim is to identify the susceptibility gene. Two approaches are the prediction of candidate genes and/or the determination of a physical map of the region.
AB - To determine the role of genetics in bipolar affective disorders it was necessary to have correct diagnosis and large homogenous population(s). To identify a marker linked to the disease two additional factors were important, a correct model for genetic transmission and highly polymorphic DNA markers. With the establishment of a linked marker the aim is to identify the susceptibility gene. Two approaches are the prediction of candidate genes and/or the determination of a physical map of the region.
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UR - http://www.scopus.com/inward/citedby.url?scp=0023520176&partnerID=8YFLogxK
U2 - 10.1016/0022-3956(87)90106-3
DO - 10.1016/0022-3956(87)90106-3
M3 - Article
C2 - 2894460
AN - SCOPUS:0023520176
VL - 21
SP - 569
EP - 575
JO - Journal of Psychiatric Research
JF - Journal of Psychiatric Research
SN - 0022-3956
IS - 4
ER -