Abstract
To determine the role of genetics in bipolar affective disorders it was necessary to have correct diagnosis and large homogenous population(s). To identify a marker linked to the disease two additional factors were important, a correct model for genetic transmission and highly polymorphic DNA markers. With the establishment of a linked marker the aim is to identify the susceptibility gene. Two approaches are the prediction of candidate genes and/or the determination of a physical map of the region.
Original language | English (US) |
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Pages (from-to) | 569-575 |
Number of pages | 7 |
Journal | Journal of Psychiatric Research |
Volume | 21 |
Issue number | 4 |
DOIs | |
State | Published - 1987 |
ASJC Scopus subject areas
- Psychiatry and Mental health
- Biological Psychiatry