Screening of mouse connexin 31 genomic clone and mapping by fluorescence in situ hybridization

W. Z. Li, Z. G. Xue, G. Wang

Research output: Contribution to journalArticle

Abstract

Connexin 31(Cx31) is one of the human genetic deafness disease genes. To determine the structure and function of Cx31 gene of mouse, the mouse Cx31 gene clone was screened from the genomic library with the probe obtained according to the sequence of the mouse Cx31 gene cDNA. Cx31 gene was mapped to the center of mouse chromosome 4 by fluorescence in situ hybridization. The present study lays a foundation for researches on structure and function of Cx31 gene, as well as establishment of the relative transgenic mice and gene knockout mice.

Original languageEnglish (US)
Pages (from-to)499-501
Number of pages3
JournalHunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University
Volume26
Issue number6
StatePublished - Dec 28 2001
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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