Scintigraphic visualization of an epigastric sentinel node in recurrent breast cancer after lumpectomy and postoperative radiation therapy

Renata Milardovic, Ivan Castellon, Christopher Mills, M. Erkan Altinyay, Barbara Raphael, Hussein M. Abdel-Dayem

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Sentinel node imaging and biopsy have become standard procedures for staging early breast cancer. Positive sentinel lymph node (SLN) biopsy necessitates the need for axillary lymph node dissection (ALND). Failure to visualize a sentinel lymph node in recurrent breast cancer after treatment by surgery, chemotherapy, and high-dose postoperative radiation therapy is almost the case in every patient. The reason for failure to visualize the sentinel node is the fibrosis that follows high-dose radiotherapy and blocks the lymphatics preventing spread of the tumor cells to the lymph nodes. Alternative pathways for the drainage of lymph from the breast are developed in these patients. We have previously reported on the alternative pathways of lymphatics to the contralateral axilla, supraclavicular area, and also reported on the development of intramammary lymph nodes. In this report, we are presenting another alternative pathway of lymphatics to the region of the epigastrium below the lower end of the sternum.

Original languageEnglish
Pages (from-to)207-208
Number of pages2
JournalClinical Nuclear Medicine
Volume31
Issue number4
DOIs
StatePublished - Apr 1 2006
Externally publishedYes

Fingerprint

Segmental Mastectomy
Radiotherapy
Lymph Nodes
Lymphatic Irradiation
Breast Neoplasms
Sentinel Lymph Node Biopsy
Sternum
Axilla
Lymph
Lymph Node Excision
Drainage
Breast
Fibrosis
Biopsy
Drug Therapy
Neoplasms
cyhalothrin
Therapeutics
Sentinel Lymph Node

Keywords

  • Breast cancer
  • Epigastrium
  • Lymphoscintigraphy
  • Sentinel lymph node
  • Tc-99m sulfur colloid

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Scintigraphic visualization of an epigastric sentinel node in recurrent breast cancer after lumpectomy and postoperative radiation therapy. / Milardovic, Renata; Castellon, Ivan; Mills, Christopher; Altinyay, M. Erkan; Raphael, Barbara; Abdel-Dayem, Hussein M.

In: Clinical Nuclear Medicine, Vol. 31, No. 4, 01.04.2006, p. 207-208.

Research output: Contribution to journalArticle

Milardovic, Renata ; Castellon, Ivan ; Mills, Christopher ; Altinyay, M. Erkan ; Raphael, Barbara ; Abdel-Dayem, Hussein M. / Scintigraphic visualization of an epigastric sentinel node in recurrent breast cancer after lumpectomy and postoperative radiation therapy. In: Clinical Nuclear Medicine. 2006 ; Vol. 31, No. 4. pp. 207-208.
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