The scanning electron microscope allows immediate high magnification, three-dimensional viewing. With this new instrument the trabecular meshwork of human and primate specimens was examined and compared. While there were some apparent minor species variations, the overall pattern was the same. The trabecular meshwork consisted of a uveal portion with large openings, a corneoscleral portion with smaller openings, and a juxtacanalicular portion without apparent openings. In the monkey, unlike the human, the "trabecular sheets" in the corneoscleral portion were formed in large part by cellular extensions, rather than being entirely made up of endothelial-lined connective tissue trabeculae. Cyst-like vacuoles in the endothelial lining of Schlemm's canal were seen in some specimens.
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