Sarcoma molecular testing: Diagnosis and prognosis

Alexander J.F. Lazar, Jonathan C. Trent

Research output: Contribution to journalReview article

7 Scopus citations

Abstract

Methodologies employed in the rapidly developing field of soft tissue sarcoma molecular testing focus primarily on diagnosis using chromosomal translocations and the resulting fusion transcripts. Molecular prognostic testing holds promise in this complex group of rare mesenchymal malignancies, but results are preliminary and require further confirmation. Analysis of activating KIT mutations in gastrointestinal stromal tumors is currently being used in management of patient therapy.

Original languageEnglish (US)
Pages (from-to)309-315
Number of pages7
JournalCurrent oncology reports
Volume9
Issue number4
DOIs
StatePublished - Jul 1 2007

ASJC Scopus subject areas

  • Oncology

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