Salience processing and insular cortical function and dysfunction

Research output: Contribution to journalArticle

545 Citations (Scopus)

Abstract

The brain is constantly bombarded by stimuli, and the relative salience of these inputs determines which are more likely to capture attention. A brain system known as the 'salience network', with key nodes in the insular cortices, has a central role in the detection of behaviourally relevant stimuli and the coordination of neural resources. Emerging evidence suggests that atypical engagement of specific subdivisions of the insula within the salience network is a feature of many neuropsychiatric disorders.

Original languageEnglish (US)
Pages (from-to)55-61
Number of pages7
JournalNature Reviews Neuroscience
Volume16
Issue number1
DOIs
StatePublished - Dec 19 2014

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Brain
Cerebral Cortex

ASJC Scopus subject areas

  • Neuroscience(all)
  • Medicine(all)

Cite this

Salience processing and insular cortical function and dysfunction. / Uddin, Lucina Q.

In: Nature Reviews Neuroscience, Vol. 16, No. 1, 19.12.2014, p. 55-61.

Research output: Contribution to journalArticle

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