Safety considerations when using drugs to treat pruritus

Kayla Fourzali, Gil Yosipovitch

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations


Introduction: Treatment for chronic pruritus ranges from use of topical formulations to newer biologic agents. Targeting treatment to the underlying etiology is key in reducing the burden of disease while avoiding systemic or adverse effects. Areas covered: This review details the effective medical treatments used in various etiologies of chronic itch with a focus on the potential adverse effects and safety data available for each. Expert opinion: New drug developments in the areas of neural signaling and immune targeting show great promise for the future of chronic itch treatment. These new therapies broaden the available treatment options but also pose new considerations for safety and adverse effects.

Original languageEnglish (US)
Pages (from-to)467-477
Number of pages11
JournalExpert Opinion on Drug Safety
Issue number4
StatePublished - Apr 2 2020


  • Safety
  • itch
  • pruritus
  • treatment

ASJC Scopus subject areas

  • Pharmacology (medical)


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