Safety and Efficacy of Diode Laser Transscleral Cyclophotocoagulation in Eyes with Good Visual Acuity

Parth Shah, Amitabha Bhakta, Elizabeth A. Vanner, Krishna S. Kishor, David S. Greenfield, Arindel S.R. Maharaj

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

Background/Aims: To evaluate the safety and efficacy of diode laser transscleral cyclophotocoagulation (TSCPC) in eyes with good visual acuity. Methods: A retrospective chart review identified patients that underwent TSCPC for uncontrolled intraocular pressure (IOP) from 2014 to 2016. Enrollment criteria included pre-treatment best-corrected Snellen visual acuity (BCVA) of 20/40 or better, and a minimum of 6 months of postoperative follow-up. Results: Thirty-three eyes of 33 patients (mean age 72.1±16.0y) were enrolled (mean follow-up 12.6±6.1mo). The mean (SD) IOP was reduced 48.3% from 27.1mmHg (7.8) at baseline to 13.1mmHg (4.2) at last follow-up. Reduction of 1 or more glaucoma medications was achieved in 17 eyes (51.5%) at last-follow-up. The cumulative probability of complete success (BCVA loss < 2 Snellen lines, 20% reduction IOP, no reoperation for glaucoma, no IOP <5mmHg) was 78.8% and 50% at months 6 and 12, respectively. The cumulative probability of qualified success (BCVA ≥2 lines with ≥20% reduction IOP, no reoperation for glaucoma, no IOP <5mmHg) was 90.1% and 81.3% at month six and one year respectively. Significant vision loss, defined as BCVA ≥2 lines, occurred in 33% of patients. The most common complications were post-operative iritis (56.3%)and cystoid macular edema (CME) (12.5%). Conclusions: TSCPC demonstrates a strong reduction in intraocular pressure and glaucoma medication use. However, with significant vision loss in 33% of patients, future prospective studies with a comparison group receiving traditional glaucoma surgery are needed to determine comparative safety and efficacy.

Original languageEnglish (US)
JournalJournal of Glaucoma
DOIs
StateAccepted/In press - Jan 1 2018

Keywords

  • cyclodestruction
  • diode laser
  • transscleral cyclophotocoagulation
  • visual acuity

ASJC Scopus subject areas

  • Ophthalmology

Fingerprint Dive into the research topics of 'Safety and Efficacy of Diode Laser Transscleral Cyclophotocoagulation in Eyes with Good Visual Acuity'. Together they form a unique fingerprint.

Cite this