Abstract
Remitting seronegative symmetrical synovitis with pitting edema or RS3PE is a rare elderly-onset rheumatic syndrome. Although there are overlapping clinical manifestations between RS3PE, elderly-onset rheumatoid arthritis, and polymyalgia rheumatica, RS3PE has distinct characteristics. RS3PE can be associated with neoplasia and various rheumatic conditions, suggesting that it may be heterogeneous, and is considered as a paraneoplastic rheumatic disease. The pathogenesis of RS3PE may involve vascular endothelial growth factor and infection in RS3PE based upon limited data. Patients with RS3PE without concomitant malignancy respond well to small doses of glucocorticoids and carry good prognosis.
| Original language | English (US) |
|---|---|
| Article number | 49 |
| Journal | Current Rheumatology Reports |
| Volume | 17 |
| Issue number | 8 |
| DOIs | |
| State | Published - Aug 27 2015 |
| Externally published | Yes |
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Keywords
- Infection
- Neoplasm
- Polymyalgia rheumatica
- Rheumatoid arthritis
- RS3PE
- Vascular endothelial growth factor
ASJC Scopus subject areas
- Rheumatology
Cite this
RS3PE : Clinical and Research Development. / Li, Hongbin; Altman, Roy D; Yao, Qingping.
In: Current Rheumatology Reports, Vol. 17, No. 8, 49, 27.08.2015.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - RS3PE
T2 - Clinical and Research Development
AU - Li, Hongbin
AU - Altman, Roy D
AU - Yao, Qingping
PY - 2015/8/27
Y1 - 2015/8/27
N2 - Remitting seronegative symmetrical synovitis with pitting edema or RS3PE is a rare elderly-onset rheumatic syndrome. Although there are overlapping clinical manifestations between RS3PE, elderly-onset rheumatoid arthritis, and polymyalgia rheumatica, RS3PE has distinct characteristics. RS3PE can be associated with neoplasia and various rheumatic conditions, suggesting that it may be heterogeneous, and is considered as a paraneoplastic rheumatic disease. The pathogenesis of RS3PE may involve vascular endothelial growth factor and infection in RS3PE based upon limited data. Patients with RS3PE without concomitant malignancy respond well to small doses of glucocorticoids and carry good prognosis.
AB - Remitting seronegative symmetrical synovitis with pitting edema or RS3PE is a rare elderly-onset rheumatic syndrome. Although there are overlapping clinical manifestations between RS3PE, elderly-onset rheumatoid arthritis, and polymyalgia rheumatica, RS3PE has distinct characteristics. RS3PE can be associated with neoplasia and various rheumatic conditions, suggesting that it may be heterogeneous, and is considered as a paraneoplastic rheumatic disease. The pathogenesis of RS3PE may involve vascular endothelial growth factor and infection in RS3PE based upon limited data. Patients with RS3PE without concomitant malignancy respond well to small doses of glucocorticoids and carry good prognosis.
KW - Infection
KW - Neoplasm
KW - Polymyalgia rheumatica
KW - Rheumatoid arthritis
KW - RS3PE
KW - Vascular endothelial growth factor
UR - http://www.scopus.com/inward/record.url?scp=84932634964&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84932634964&partnerID=8YFLogxK
U2 - 10.1007/s11926-015-0525-0
DO - 10.1007/s11926-015-0525-0
M3 - Article
VL - 17
JO - Current Rheumatology Reports
JF - Current Rheumatology Reports
SN - 1523-3774
IS - 8
M1 - 49
ER -