Role of Ovarian Suspension in Preventing Postsurgical Ovarian Adhesions in Patients with Stage III-IV Pelvic Endometriosis: A Systematic Review

Pierluigi Giampaolino, Luigi Della Corte, Gabriele Saccone, Amerigo Vitagliano, Giuseppe Bifulco, Gloria Calagna, Jose Carugno, Attilio Di Spiezio Sardo

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Endometriosis is a benign complex gynecologic condition with high morbidity that affects women of reproductive age. Pelvic adhesion formation represents a serious clinical challenge in the management of patients with endometriosis. Several interventions aimed at reducing postoperative ovarian adhesion formation have been proposed in recent years. Here we summarize the published evidence on the efficacy of ovarian suspension in preventing postoperative ovarian adhesion formation in women undergoing laparoscopic surgery for stage III-IV endometriosis. The research was conducted using electronic databases. A review of the abstracts of all references retrieved from the search was conducted. Selection criteria for the systematic review included all randomized controlled trials (RCTs) and nonrandomized studies (NRSs) of premenopausal women diagnosed with stage III-IV pelvic endometriosis who underwent ovarian suspension or no ovarian suspension (control group). The RCTs were eligible for meta-analysis. Eight studies, 2 RCTs and 6 NRSs, were included in the systematic review. In all 8 studies, ovarian suspension was performed during surgery for stage III-IV endometriosis. The site of the suspension was the anterior abdominal wall in 76.8% of the cases. Five studies reported the use of polypropylene as suture for the suspension. Removal of the suspension suture in the postoperative period was reported in 6 studies. Pooled data from a meta-analysis of the RCTs show that women who underwent ovarian suspension had a significantly lower incidence of postoperative adhesion formation, particularly of moderate to severe adhesions. Ovarian suspension may reduce the rate and severity of postoperative adhesions formation in women undergoing laparoscopy for the treatment of stage III-IV endometriosis; however, RCTs with larger sample sizes are needed.

Original languageEnglish (US)
JournalJournal of Minimally Invasive Gynecology
DOIs
StateAccepted/In press - Jan 1 2018

Fingerprint

Endometriosis
Suspensions
Randomized Controlled Trials
Laparoscopy
Sutures
Meta-Analysis
Polypropylenes
Abdominal Wall
Postoperative Period
Sample Size
Patient Selection
Databases
Morbidity
Control Groups
Incidence
Research

Keywords

  • Endometriosis
  • Minimally invasive gynecologic surgery
  • Ovarian suspension Postoperative ovarian adhesions

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Role of Ovarian Suspension in Preventing Postsurgical Ovarian Adhesions in Patients with Stage III-IV Pelvic Endometriosis : A Systematic Review. / Giampaolino, Pierluigi; Della Corte, Luigi; Saccone, Gabriele; Vitagliano, Amerigo; Bifulco, Giuseppe; Calagna, Gloria; Carugno, Jose; Di Spiezio Sardo, Attilio.

In: Journal of Minimally Invasive Gynecology, 01.01.2018.

Research output: Contribution to journalArticle

Giampaolino, Pierluigi ; Della Corte, Luigi ; Saccone, Gabriele ; Vitagliano, Amerigo ; Bifulco, Giuseppe ; Calagna, Gloria ; Carugno, Jose ; Di Spiezio Sardo, Attilio. / Role of Ovarian Suspension in Preventing Postsurgical Ovarian Adhesions in Patients with Stage III-IV Pelvic Endometriosis : A Systematic Review. In: Journal of Minimally Invasive Gynecology. 2018.
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