Role of Histone Methylation in Myeloid Malignancies -Review

Yu Nan Li, Meng Yao Sheng, Feng-Chun Yang, Yuan Zhou

Research output: Contribution to journalReview article

Abstract

Histone methylation is one of the important epigenetic regulatory mechanisms, and plays a significant role in a variety of physiological and pathological processes. Many recent studies have shown that abnormalities of histone methylation are closely related with the initiation and progression of myeloid malignancies. The reversibility of histone methylation provides a broad prospect for the discovery and application of specific small molecule drugs. This review summarizes the recent progresses in this area and mainly focuses on the correlation of histone methylation with myeloid malignancies.

Original languageEnglish (US)
Pages (from-to)235-239
Number of pages5
JournalZhongguo shi yan xue ye xue za zhi
Volume25
Issue number1
DOIs
StatePublished - Feb 1 2017
Externally publishedYes

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ASJC Scopus subject areas

  • Medicine(all)

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