Role of endotoxin and bacteria in long-term survival of preserved small-bowel allografts

Luis H. Toledo-Pereyra, Leopoldo Raij, Richard L. Simmons, John S. Najarian

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Endotoxins are potent immunological adjuvants that can accelerate the death of unprepared canine small bowels perfused for 12 hours and then allotransplanted. Hemorrhagic necrosis was a consistent finding in the endotoxin-positive dogs. This represented either an accelerated type of rejection or intravascular coagulation-like phenomenon. The preparation of the small bowel with antibiotics led to prolongation of survival.

Original languageEnglish
Pages (from-to)474-481
Number of pages8
JournalSurgery
Volume76
Issue number3
StatePublished - Jan 1 1974
Externally publishedYes

Fingerprint

Endotoxins
Allografts
Bacteria
Immunologic Adjuvants
Canidae
Necrosis
Dogs
Anti-Bacterial Agents

ASJC Scopus subject areas

  • Surgery

Cite this

Toledo-Pereyra, L. H., Raij, L., Simmons, R. L., & Najarian, J. S. (1974). Role of endotoxin and bacteria in long-term survival of preserved small-bowel allografts. Surgery, 76(3), 474-481.

Role of endotoxin and bacteria in long-term survival of preserved small-bowel allografts. / Toledo-Pereyra, Luis H.; Raij, Leopoldo; Simmons, Richard L.; Najarian, John S.

In: Surgery, Vol. 76, No. 3, 01.01.1974, p. 474-481.

Research output: Contribution to journalArticle

Toledo-Pereyra, LH, Raij, L, Simmons, RL & Najarian, JS 1974, 'Role of endotoxin and bacteria in long-term survival of preserved small-bowel allografts', Surgery, vol. 76, no. 3, pp. 474-481.
Toledo-Pereyra LH, Raij L, Simmons RL, Najarian JS. Role of endotoxin and bacteria in long-term survival of preserved small-bowel allografts. Surgery. 1974 Jan 1;76(3):474-481.
Toledo-Pereyra, Luis H. ; Raij, Leopoldo ; Simmons, Richard L. ; Najarian, John S. / Role of endotoxin and bacteria in long-term survival of preserved small-bowel allografts. In: Surgery. 1974 ; Vol. 76, No. 3. pp. 474-481.
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