Robot-assisted partial nephrectomy in cystic tumours: Analysis of the Vattikuti Global Quality Initiative in Robotic Urologic Surgery (GQI-RUS) database

Giacomo Novara, Sabrina La Falce, Ronney Abaza, James Adshead, Rajesh Ahlawat, Nicolò Maria Buffi, Ben Challacombe, Prokar Dasgupta, Daniel A. Moon, Dipen J Parekh, Francesco Porpiglia, Sudhir Rawal, Craig Rogers, Alessandro Volpe, Mahendra Bhandari, Alexander Mottrie

Research output: Contribution to journalArticle

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Abstract

Objective To evaluate the outcomes of robot-assisted partial nephrectomy (RAPN) in cystic tumours, analysing a large, multi-institutional, retrospective series of RAPN, as limited data are available about the outcome of RAPN in cystic tumours. Patients and Methods We evaluated 465 patients who received RAPN for either cystic or solid tumours from 2010 to 2013 and included in the multi-institutional, retrospective Vattikuti Global Quality Initiative in Robotic Urologic Surgery (GQI-RUS) database. Univariable and multivariable linear and logistic regression models addressed the association of cystic tumours with perioperative outcomes. Results In all, 54 (12%) tumours were cystic. Cystic tumours were associated with significantly lower operative time (t -3.9; P <0.001), once adjusted for the effect of covariates, whereas blood loss and warm ischaemia time were similar. Postoperative any grade complications were recorded in 66 solid (16%) and nine cystic (17%) tumours (P = 0.08). In multivariable analysis, cystic tumours were not associated with a significantly lower risk of any grade postoperative complications [odds ratio (OR) 0.9; P = 0.8]. Similarly, presence of tumours with cystic features was not associated with a significantly different risk of high-grade postoperative complications (OR 2.2; P = 0.1). Prevalence of cancer histology and positive surgical margin rates were similar in cystic and solid tumours. Cystic tumours were not associated with significantly different postoperative estimated glomerular filtration rate (t 0.4; P = 0.7), once adjusted for the effect of covariates. Conclusions RAPN can be performed in cystic renal tumours with perioperative, pathological, and functional outcomes similar to those achievable in solid tumours.

Original languageEnglish (US)
Pages (from-to)642-647
Number of pages6
JournalBJU International
Volume117
Issue number4
DOIs
StatePublished - Apr 1 2016

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Robotics
Nephrectomy
Databases
Neoplasms
Logistic Models
Odds Ratio
Warm Ischemia
Operative Time
Glomerular Filtration Rate
Linear Models
Histology

Keywords

  • cystic tumour
  • kidney
  • partial nephrectomy
  • renal cell carcinoma (RCC)

ASJC Scopus subject areas

  • Urology

Cite this

Robot-assisted partial nephrectomy in cystic tumours : Analysis of the Vattikuti Global Quality Initiative in Robotic Urologic Surgery (GQI-RUS) database. / Novara, Giacomo; La Falce, Sabrina; Abaza, Ronney; Adshead, James; Ahlawat, Rajesh; Buffi, Nicolò Maria; Challacombe, Ben; Dasgupta, Prokar; Moon, Daniel A.; Parekh, Dipen J; Porpiglia, Francesco; Rawal, Sudhir; Rogers, Craig; Volpe, Alessandro; Bhandari, Mahendra; Mottrie, Alexander.

In: BJU International, Vol. 117, No. 4, 01.04.2016, p. 642-647.

Research output: Contribution to journalArticle

Novara, G, La Falce, S, Abaza, R, Adshead, J, Ahlawat, R, Buffi, NM, Challacombe, B, Dasgupta, P, Moon, DA, Parekh, DJ, Porpiglia, F, Rawal, S, Rogers, C, Volpe, A, Bhandari, M & Mottrie, A 2016, 'Robot-assisted partial nephrectomy in cystic tumours: Analysis of the Vattikuti Global Quality Initiative in Robotic Urologic Surgery (GQI-RUS) database', BJU International, vol. 117, no. 4, pp. 642-647. https://doi.org/10.1111/bju.13256
Novara, Giacomo ; La Falce, Sabrina ; Abaza, Ronney ; Adshead, James ; Ahlawat, Rajesh ; Buffi, Nicolò Maria ; Challacombe, Ben ; Dasgupta, Prokar ; Moon, Daniel A. ; Parekh, Dipen J ; Porpiglia, Francesco ; Rawal, Sudhir ; Rogers, Craig ; Volpe, Alessandro ; Bhandari, Mahendra ; Mottrie, Alexander. / Robot-assisted partial nephrectomy in cystic tumours : Analysis of the Vattikuti Global Quality Initiative in Robotic Urologic Surgery (GQI-RUS) database. In: BJU International. 2016 ; Vol. 117, No. 4. pp. 642-647.
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abstract = "Objective To evaluate the outcomes of robot-assisted partial nephrectomy (RAPN) in cystic tumours, analysing a large, multi-institutional, retrospective series of RAPN, as limited data are available about the outcome of RAPN in cystic tumours. Patients and Methods We evaluated 465 patients who received RAPN for either cystic or solid tumours from 2010 to 2013 and included in the multi-institutional, retrospective Vattikuti Global Quality Initiative in Robotic Urologic Surgery (GQI-RUS) database. Univariable and multivariable linear and logistic regression models addressed the association of cystic tumours with perioperative outcomes. Results In all, 54 (12{\%}) tumours were cystic. Cystic tumours were associated with significantly lower operative time (t -3.9; P <0.001), once adjusted for the effect of covariates, whereas blood loss and warm ischaemia time were similar. Postoperative any grade complications were recorded in 66 solid (16{\%}) and nine cystic (17{\%}) tumours (P = 0.08). In multivariable analysis, cystic tumours were not associated with a significantly lower risk of any grade postoperative complications [odds ratio (OR) 0.9; P = 0.8]. Similarly, presence of tumours with cystic features was not associated with a significantly different risk of high-grade postoperative complications (OR 2.2; P = 0.1). Prevalence of cancer histology and positive surgical margin rates were similar in cystic and solid tumours. Cystic tumours were not associated with significantly different postoperative estimated glomerular filtration rate (t 0.4; P = 0.7), once adjusted for the effect of covariates. Conclusions RAPN can be performed in cystic renal tumours with perioperative, pathological, and functional outcomes similar to those achievable in solid tumours.",
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T1 - Robot-assisted partial nephrectomy in cystic tumours

T2 - Analysis of the Vattikuti Global Quality Initiative in Robotic Urologic Surgery (GQI-RUS) database

AU - Novara, Giacomo

AU - La Falce, Sabrina

AU - Abaza, Ronney

AU - Adshead, James

AU - Ahlawat, Rajesh

AU - Buffi, Nicolò Maria

AU - Challacombe, Ben

AU - Dasgupta, Prokar

AU - Moon, Daniel A.

AU - Parekh, Dipen J

AU - Porpiglia, Francesco

AU - Rawal, Sudhir

AU - Rogers, Craig

AU - Volpe, Alessandro

AU - Bhandari, Mahendra

AU - Mottrie, Alexander

PY - 2016/4/1

Y1 - 2016/4/1

N2 - Objective To evaluate the outcomes of robot-assisted partial nephrectomy (RAPN) in cystic tumours, analysing a large, multi-institutional, retrospective series of RAPN, as limited data are available about the outcome of RAPN in cystic tumours. Patients and Methods We evaluated 465 patients who received RAPN for either cystic or solid tumours from 2010 to 2013 and included in the multi-institutional, retrospective Vattikuti Global Quality Initiative in Robotic Urologic Surgery (GQI-RUS) database. Univariable and multivariable linear and logistic regression models addressed the association of cystic tumours with perioperative outcomes. Results In all, 54 (12%) tumours were cystic. Cystic tumours were associated with significantly lower operative time (t -3.9; P <0.001), once adjusted for the effect of covariates, whereas blood loss and warm ischaemia time were similar. Postoperative any grade complications were recorded in 66 solid (16%) and nine cystic (17%) tumours (P = 0.08). In multivariable analysis, cystic tumours were not associated with a significantly lower risk of any grade postoperative complications [odds ratio (OR) 0.9; P = 0.8]. Similarly, presence of tumours with cystic features was not associated with a significantly different risk of high-grade postoperative complications (OR 2.2; P = 0.1). Prevalence of cancer histology and positive surgical margin rates were similar in cystic and solid tumours. Cystic tumours were not associated with significantly different postoperative estimated glomerular filtration rate (t 0.4; P = 0.7), once adjusted for the effect of covariates. Conclusions RAPN can be performed in cystic renal tumours with perioperative, pathological, and functional outcomes similar to those achievable in solid tumours.

AB - Objective To evaluate the outcomes of robot-assisted partial nephrectomy (RAPN) in cystic tumours, analysing a large, multi-institutional, retrospective series of RAPN, as limited data are available about the outcome of RAPN in cystic tumours. Patients and Methods We evaluated 465 patients who received RAPN for either cystic or solid tumours from 2010 to 2013 and included in the multi-institutional, retrospective Vattikuti Global Quality Initiative in Robotic Urologic Surgery (GQI-RUS) database. Univariable and multivariable linear and logistic regression models addressed the association of cystic tumours with perioperative outcomes. Results In all, 54 (12%) tumours were cystic. Cystic tumours were associated with significantly lower operative time (t -3.9; P <0.001), once adjusted for the effect of covariates, whereas blood loss and warm ischaemia time were similar. Postoperative any grade complications were recorded in 66 solid (16%) and nine cystic (17%) tumours (P = 0.08). In multivariable analysis, cystic tumours were not associated with a significantly lower risk of any grade postoperative complications [odds ratio (OR) 0.9; P = 0.8]. Similarly, presence of tumours with cystic features was not associated with a significantly different risk of high-grade postoperative complications (OR 2.2; P = 0.1). Prevalence of cancer histology and positive surgical margin rates were similar in cystic and solid tumours. Cystic tumours were not associated with significantly different postoperative estimated glomerular filtration rate (t 0.4; P = 0.7), once adjusted for the effect of covariates. Conclusions RAPN can be performed in cystic renal tumours with perioperative, pathological, and functional outcomes similar to those achievable in solid tumours.

KW - cystic tumour

KW - kidney

KW - partial nephrectomy

KW - renal cell carcinoma (RCC)

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