Rituximab Treatment for Relapsed Autoimmune Hemolytic Anemia in Evans Syndrome

Anat Galor; Timothy O'Brien

doi:10.1007/BF02983558

Rituximab Treatment for Relapsed Autoimmune Hemolytic Anemia in Evans Syndrome

Anat Galor, Timothy O'Brien

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

A case is reported of idiopathic relapsed autoimmune hemolytic anemia successfully treated with rituximab. A 43-year-old white male patient with past medical history of Evans syndrome was found to have recurrent autoimmune hemolytic anemia. Previous treatments included steroids, splenectomy, intravenous immunoglobulin, plasmapheresis, staphylococcal Protein A immunoadsorption (Prosorba column), and chemotherapeutic agents (cytoxan and vincristine). Rituximab was given weekly at 375 mg/m² for 4 doses. The drug was well tolerated and the patient remains in remission 9 months after completion of therapy.

Original language	English (US)
Pages (from-to)	335-336
Number of pages	2
Journal	International journal of hematology
Volume	78
Issue number	4
DOIs	https://doi.org/10.1007/BF02983558
State	Published - Nov 2003
Externally published	Yes

Keywords

Immune hemolytic anemia
Rituximab

ASJC Scopus subject areas

Hematology

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10.1007/BF02983558

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abstract = "A case is reported of idiopathic relapsed autoimmune hemolytic anemia successfully treated with rituximab. A 43-year-old white male patient with past medical history of Evans syndrome was found to have recurrent autoimmune hemolytic anemia. Previous treatments included steroids, splenectomy, intravenous immunoglobulin, plasmapheresis, staphylococcal Protein A immunoadsorption (Prosorba column), and chemotherapeutic agents (cytoxan and vincristine). Rituximab was given weekly at 375 mg/m2 for 4 doses. The drug was well tolerated and the patient remains in remission 9 months after completion of therapy.",

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AB - A case is reported of idiopathic relapsed autoimmune hemolytic anemia successfully treated with rituximab. A 43-year-old white male patient with past medical history of Evans syndrome was found to have recurrent autoimmune hemolytic anemia. Previous treatments included steroids, splenectomy, intravenous immunoglobulin, plasmapheresis, staphylococcal Protein A immunoadsorption (Prosorba column), and chemotherapeutic agents (cytoxan and vincristine). Rituximab was given weekly at 375 mg/m2 for 4 doses. The drug was well tolerated and the patient remains in remission 9 months after completion of therapy.

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KW - Rituximab

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Rituximab Treatment for Relapsed Autoimmune Hemolytic Anemia in Evans Syndrome

Abstract

Keywords

ASJC Scopus subject areas

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