Abstract
We sought to determine whether twin gestations with an anomalous fetus are at increased risk of preterm delivery or intrauterine growth restriction (IUGR) compared to twins with 2 normal fetuses. This was a retrospective cohort of twins undergoing ultrasound 15-22 weeks' gestation. Groups were defined by the presence of 1 twin with a major anomaly (discordant) or by twins with no major anomalies (normal). The primary outcomes were preterm delivery (<37 weeks) and IUGR (<10th percentile). Of 1977 twin pregnancies, 66 had a twin with a major anomaly. Preterm delivery occurred in 42 (63.6%) discordant twins, compared to 1271 (66.5%) normal twins (risk ratio, 1.0; 95% confidence interval, 0.81.2). IUGR was diagnosed in 15 (22.7%) normal co-twins, compared to 406 (21.3%) presenting twins in normal twins (risk ratio, 1.1; 95% confidence interval, 0.71.7). Twins discordant for major anomalies are not at increased risk of preterm delivery or IUGR compared to twins with no major anomalies.
Original language | English (US) |
---|---|
Pages (from-to) | 70.e1-70.e5 |
Journal | American journal of obstetrics and gynecology |
Volume | 206 |
Issue number | 1 |
DOIs | |
State | Published - Jan 2012 |
Externally published | Yes |
Keywords
- anomalies
- intrauterine growth restriction
- multiple gestation
- preterm delivery
ASJC Scopus subject areas
- Obstetrics and Gynecology