Risk factors for central serous chorioretinopathy: A case-control study

Robert Haimovici, Sean Koh, David R. Gagnon, Todd Lehrfeld, Sarah Wellik

Research output: Contribution to journalArticle

255 Citations (Scopus)

Abstract

Purpose: To identify systemic factors associated with the development of central serous chorioretinopathy (CSCR). Design: Retrospective, case-control study. Participants and controls: 312 cases and 312 controls. Results: By use of a multivariate analysis, the previously described risk factors, systemic steroid use (odds ratio [OR], 37.1; 95% confidence interval [CI], 6.2-221.8), and pregnancy (OR, 7.1; 95% CI, 1.0-50.7), were strongly associated with CSCR. Additional risk factors identified by this study include antibiotic use (OR, 6.2; 95% CI, 1.0-37.9), alcohol use (OR, 4.9; 95% CI, 1.5-16.3), untreated hypertension (OR, 3.3; 95% CI, 1.3-8.5), and allergic respiratory disease (OR, 2.5; 95% CI, 1.2-5.1). Conclusions: A wide variety of systemic factors are associated with CSCR. Prospective studies are warranted to evaluate the nature and significance of these associations further.

Original languageEnglish
Pages (from-to)244-249
Number of pages6
JournalOphthalmology
Volume111
Issue number2
DOIs
StatePublished - Feb 1 2004
Externally publishedYes

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Central Serous Chorioretinopathy
Case-Control Studies
Odds Ratio
Confidence Intervals
Multivariate Analysis
Steroids
Alcohols
Prospective Studies
Anti-Bacterial Agents
Hypertension
Pregnancy

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Risk factors for central serous chorioretinopathy : A case-control study. / Haimovici, Robert; Koh, Sean; Gagnon, David R.; Lehrfeld, Todd; Wellik, Sarah.

In: Ophthalmology, Vol. 111, No. 2, 01.02.2004, p. 244-249.

Research output: Contribution to journalArticle

Haimovici, Robert ; Koh, Sean ; Gagnon, David R. ; Lehrfeld, Todd ; Wellik, Sarah. / Risk factors for central serous chorioretinopathy : A case-control study. In: Ophthalmology. 2004 ; Vol. 111, No. 2. pp. 244-249.
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