TY - JOUR
T1 - Risk factors for central serous chorioretinopathy
T2 - A case-control study
AU - Haimovici, Robert
AU - Koh, Sean
AU - Gagnon, David R.
AU - Lehrfeld, Todd
AU - Wellik, Sarah
N1 - Funding Information:
Supported by The Macula Foundation, New York; The Richard H. Chartrand Foundation; Research to Prevent Blindness; and The Massachusetts Lions Eye Research Fund.
PY - 2004/2
Y1 - 2004/2
N2 - Purpose: To identify systemic factors associated with the development of central serous chorioretinopathy (CSCR). Design: Retrospective, case-control study. Participants and controls: 312 cases and 312 controls. Results: By use of a multivariate analysis, the previously described risk factors, systemic steroid use (odds ratio [OR], 37.1; 95% confidence interval [CI], 6.2-221.8), and pregnancy (OR, 7.1; 95% CI, 1.0-50.7), were strongly associated with CSCR. Additional risk factors identified by this study include antibiotic use (OR, 6.2; 95% CI, 1.0-37.9), alcohol use (OR, 4.9; 95% CI, 1.5-16.3), untreated hypertension (OR, 3.3; 95% CI, 1.3-8.5), and allergic respiratory disease (OR, 2.5; 95% CI, 1.2-5.1). Conclusions: A wide variety of systemic factors are associated with CSCR. Prospective studies are warranted to evaluate the nature and significance of these associations further.
AB - Purpose: To identify systemic factors associated with the development of central serous chorioretinopathy (CSCR). Design: Retrospective, case-control study. Participants and controls: 312 cases and 312 controls. Results: By use of a multivariate analysis, the previously described risk factors, systemic steroid use (odds ratio [OR], 37.1; 95% confidence interval [CI], 6.2-221.8), and pregnancy (OR, 7.1; 95% CI, 1.0-50.7), were strongly associated with CSCR. Additional risk factors identified by this study include antibiotic use (OR, 6.2; 95% CI, 1.0-37.9), alcohol use (OR, 4.9; 95% CI, 1.5-16.3), untreated hypertension (OR, 3.3; 95% CI, 1.3-8.5), and allergic respiratory disease (OR, 2.5; 95% CI, 1.2-5.1). Conclusions: A wide variety of systemic factors are associated with CSCR. Prospective studies are warranted to evaluate the nature and significance of these associations further.
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U2 - 10.1016/j.ophtha.2003.09.024
DO - 10.1016/j.ophtha.2003.09.024
M3 - Article
C2 - 15019370
AN - SCOPUS:0842310443
VL - 111
SP - 244
EP - 249
JO - Ophthalmology
JF - Ophthalmology
SN - 0161-6420
IS - 2
ER -