Risk factors and clinical manifestations of pathologically verified lacunar infarctions

M. H. Tuszynski, Carol Petito, D. E. Levy

Research output: Contribution to journalArticle

116 Citations (Scopus)

Abstract

Review of 2,859 autopsy reports disclosed lacunar infarction in 169 patients (6%). Review of the charts of 167 of these patients revealed hypertension in 64%, diabetes in 34%, smoking in 46%, and no known risk factor for cerebrovascular disease in 18%. As many as 81% of the patients with lacunes were asymptomatic. Symptomatic lacunes presented most commonly as pure motor hemiparesis (31%), aphasia plus right hemiparesis (20%), or sensorimotor dysfunction (11%); none presented as pure sensory stroke. These results suggest that the spectrum of lacunar infarction is more heterogeneous than previously thought. Most lacunar are asymptomatic, and the majority of symptomatic patients do not present with 'classical' lacunar syndromes.

Original languageEnglish
Pages (from-to)990-999
Number of pages10
JournalStroke
Volume20
Issue number8
StatePublished - Jan 1 1989
Externally publishedYes

Fingerprint

Lacunar Stroke
Paresis
Cerebrovascular Disorders
Aphasia
Autopsy
Smoking
Stroke
Hypertension

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Neuroscience(all)

Cite this

Tuszynski, M. H., Petito, C., & Levy, D. E. (1989). Risk factors and clinical manifestations of pathologically verified lacunar infarctions. Stroke, 20(8), 990-999.

Risk factors and clinical manifestations of pathologically verified lacunar infarctions. / Tuszynski, M. H.; Petito, Carol; Levy, D. E.

In: Stroke, Vol. 20, No. 8, 01.01.1989, p. 990-999.

Research output: Contribution to journalArticle

Tuszynski, MH, Petito, C & Levy, DE 1989, 'Risk factors and clinical manifestations of pathologically verified lacunar infarctions', Stroke, vol. 20, no. 8, pp. 990-999.
Tuszynski MH, Petito C, Levy DE. Risk factors and clinical manifestations of pathologically verified lacunar infarctions. Stroke. 1989 Jan 1;20(8):990-999.
Tuszynski, M. H. ; Petito, Carol ; Levy, D. E. / Risk factors and clinical manifestations of pathologically verified lacunar infarctions. In: Stroke. 1989 ; Vol. 20, No. 8. pp. 990-999.
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