Abstract
Review of 2,859 autopsy reports disclosed lacunar infarction in 169 patients (6%). Review of the charts of 167 of these patients revealed hypertension in 64%, diabetes in 34%, smoking in 46%, and no known risk factor for cerebrovascular disease in 18%. As many as 81% of the patients with lacunes were asymptomatic. Symptomatic lacunes presented most commonly as pure motor hemiparesis (31%), aphasia plus right hemiparesis (20%), or sensorimotor dysfunction (11%); none presented as pure sensory stroke. These results suggest that the spectrum of lacunar infarction is more heterogeneous than previously thought. Most lacunar are asymptomatic, and the majority of symptomatic patients do not present with 'classical' lacunar syndromes.
| Original language | English |
|---|---|
| Pages (from-to) | 990-999 |
| Number of pages | 10 |
| Journal | Stroke |
| Volume | 20 |
| Issue number | 8 |
| State | Published - Jan 1 1989 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
- Neuroscience(all)
Cite this
Risk factors and clinical manifestations of pathologically verified lacunar infarctions. / Tuszynski, M. H.; Petito, Carol; Levy, D. E.
In: Stroke, Vol. 20, No. 8, 01.01.1989, p. 990-999.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Risk factors and clinical manifestations of pathologically verified lacunar infarctions
AU - Tuszynski, M. H.
AU - Petito, Carol
AU - Levy, D. E.
PY - 1989/1/1
Y1 - 1989/1/1
N2 - Review of 2,859 autopsy reports disclosed lacunar infarction in 169 patients (6%). Review of the charts of 167 of these patients revealed hypertension in 64%, diabetes in 34%, smoking in 46%, and no known risk factor for cerebrovascular disease in 18%. As many as 81% of the patients with lacunes were asymptomatic. Symptomatic lacunes presented most commonly as pure motor hemiparesis (31%), aphasia plus right hemiparesis (20%), or sensorimotor dysfunction (11%); none presented as pure sensory stroke. These results suggest that the spectrum of lacunar infarction is more heterogeneous than previously thought. Most lacunar are asymptomatic, and the majority of symptomatic patients do not present with 'classical' lacunar syndromes.
AB - Review of 2,859 autopsy reports disclosed lacunar infarction in 169 patients (6%). Review of the charts of 167 of these patients revealed hypertension in 64%, diabetes in 34%, smoking in 46%, and no known risk factor for cerebrovascular disease in 18%. As many as 81% of the patients with lacunes were asymptomatic. Symptomatic lacunes presented most commonly as pure motor hemiparesis (31%), aphasia plus right hemiparesis (20%), or sensorimotor dysfunction (11%); none presented as pure sensory stroke. These results suggest that the spectrum of lacunar infarction is more heterogeneous than previously thought. Most lacunar are asymptomatic, and the majority of symptomatic patients do not present with 'classical' lacunar syndromes.
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UR - http://www.scopus.com/inward/citedby.url?scp=0024349741&partnerID=8YFLogxK
M3 - Article
C2 - 2474207
AN - SCOPUS:0024349741
VL - 20
SP - 990
EP - 999
JO - Stroke
JF - Stroke
SN - 0039-2499
IS - 8
ER -