Risk assessment and comparative effectiveness of left ventricular assist device and medical management in ambulatory heart failure patients results from the ROADMAP Study

ROADMAP Study Investigators

Research output: Contribution to journalArticle

184 Scopus citations

Abstract

Background Data for left ventricular assist devices (LVADs) in patients with noninotrope-dependent heart failure (HF) are limited. Objectives The goal of this study was to evaluate HeartMate II (HMII) LVAD support versus optimal medical management (OMM) in ambulatory New York Heart Association functional class IIIB/IV patients meeting indications for LVAD destination therapy but not dependent on intravenous inotropic support. Methods This was a prospective, multicenter (N = 41), observational study of 200 patients (97 LVAD, 103 OMM). Entry criteria included ≥ 1 hospitalization for HF in the last 12 months and 6-min walk distance (6MWD)

Original languageEnglish (US)
Pages (from-to)1747-1761
Number of pages15
JournalJournal of the American College of Cardiology
Volume66
Issue number16
DOIs
StatePublished - Oct 20 2015
Externally publishedYes

Keywords

  • functional status
  • HeartMate II
  • quality of life
  • risk/benefit analysis
  • ROADMAP

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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