Abstract
The secretion-responsive regulation of Escherichia coli secA occurs by coupling its translation to the translation and secretion of an upstream regulator, secM (formerly geneX). We revise the translational start site for secM, defining a new signal peptide sequence with an extended amino-terminal region. Mutational studies indicate that certain atypical amino acyl residues within this extended region are critical for proper secA regulation.
Original language | English (US) |
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Pages (from-to) | 5592-5595 |
Number of pages | 4 |
Journal | Journal of bacteriology |
Volume | 182 |
Issue number | 19 |
DOIs | |
State | Published - 2000 |
ASJC Scopus subject areas
- Microbiology
- Molecular Biology