Review of treatment studies of depression in HIV.

Bunmi O. Olatunji, Matthew J. Mimiaga, Conall O'Cleirigh, Steven Safren

Research output: Contribution to journalArticle

68 Citations (Scopus)

Abstract

Depression is a prevalent and interfering, yet potentially treatable illness commonly comorbid with HIV/AIDS. In HIV, symptoms and diagnoses of depression have been associated with poor adherence to antiretroviral medication regimens and to accelerated disease progression. This article is a review of the existing literature on the treatment of depression in the context of HIV, including: (1) psychosocial and behavioral health interventions that directly target Diagnostic and Statistical Manual of Mental Disorders (DSM) unipolar depressive disorders, (2) psychosocial interventions that indirectly target depressive symptoms, and (3) psychopharmacologic treatment studies for DSM-IV unipolar depressive disorders. Psychosocial and psychopharmacologic treatments of depression appear to be effective for individuals with HIV. However, additional methodologically rigorous trials are needed for definitive inferences regarding treatment efficacy. Because of the high frequency of depression comorbid with HIV, and the association of depression with important self-care behaviors in this population, identification of efficacious treatments for depression has the potential to improve both overall quality of life and, potentially, health outcomes.

Original languageEnglish (US)
Pages (from-to)112-124
Number of pages13
JournalTopics in HIV medicine : a publication of the International AIDS Society, USA
Volume14
Issue number3
StatePublished - Aug 2006
Externally publishedYes

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HIV
Depression
Therapeutics
Depressive Disorder
Diagnostic and Statistical Manual of Mental Disorders
Health
Self Care
Disease Progression
HIV-1
Acquired Immunodeficiency Syndrome
Quality of Life
Population

Cite this

Review of treatment studies of depression in HIV. / Olatunji, Bunmi O.; Mimiaga, Matthew J.; O'Cleirigh, Conall; Safren, Steven.

In: Topics in HIV medicine : a publication of the International AIDS Society, USA, Vol. 14, No. 3, 08.2006, p. 112-124.

Research output: Contribution to journalArticle

Olatunji, Bunmi O. ; Mimiaga, Matthew J. ; O'Cleirigh, Conall ; Safren, Steven. / Review of treatment studies of depression in HIV. In: Topics in HIV medicine : a publication of the International AIDS Society, USA. 2006 ; Vol. 14, No. 3. pp. 112-124.
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